Sickle cell anemia is a genetic condition that occurs because of a single point mutation in the DNA gene for hemoglobin. How is this mutation expressed in humans?

Answers

Answer 1

Answer:

Hello. Let me explain.

Explanation:

This type of anemia first of all before the Erytrocyte loses its nucleus ،at chromosome number 11 this mutation happens and valine (s type of amino acid)is replaced with glutamic acid.

Then this abnormal hemoglobins are produced in ribosomes (after transcription and translation).

This hemoglobins make a long strand which makes the RBC have a sickle shape.

This abnormal cells are very fragile.

The normal RBC is alive for about 120 days but this cells are slive for just 15 days.

This sickle shaped cells can also close blood vessels.

Macrophages destroy them so the anemia accurs.


Related Questions

PLSSS HELPPP BRAINLYIST

Answers

pretty sure that it’s B

Which statement about Venus is false ?


1. the surface temperature can melt lead.
2.It rotates clockwise on its axis .
3.Venus has an atmosphere primarily composed of Carbon Dioxide.
4. Venus is not geologically active .

Answers

Answer:

I think the false ststatement about Venus is 4

What is the function of lipids?

Answers

The following are functions of lipids:

Long term energy storage
Protection against heat loss (insulation)
Protection against physical schlock (cushion)
Protection against water loss
Chemical messengers (hormones)
Major component of membranes (phospholipids)

Which of the following occurs during telophase II? Select all that apply.

1) New nuclei begin to form
2) The centrioles pull at the chromatids
3) Chromatids arrive at opposite ends of the cell
4) Chromosomes are drawn to the metaphase plate
5) Cytoplasm divides and two daughter cells are formed

Answers

Answer: 1, 3, 5

new nuclei begin to form

chromatids arrive at opposite ends of the cell

cytoplasm divides and two daughter cells are formed

Answer:

Which of the following is the correct order of the stages of meiosis II?

prophase, metaphase, anaphase, telophase

 

Which of the following occurs during telophase II? Select all that apply.

new nuclei begin to form

chromatids arrive at opposite ends of the cell

cytoplasm divides and two daughter cells are formed

Explanation:

Help please!!!!!!!!!!!!!!!!

Answers

The answer is D because it is falsee

Answer:

D is NOT true about plants.

An enzyme acts as a catalyst to a chemical reaction by

Answers

Answer:

Speeding up chemical reactions by lowering the activation energy.

Explanation:

by lowering the activation energy

Record the etymology of biometric

Define biometric, relating it to the etymology

Relate biometrics to identify thief

Explain the role that body systems, organs, cells or tissues play in identity

Answers

Answer:

Biometrics refer to measurements and different sort of calculations related to our body. For example their is Face ID and Fingerprint for their phones to know it’s actually them.

Relate biometrics to identify thief As hackers and identity thieves have gotten more sophisticated in their practices, a password alone may not be enough to keep all our personal information completely secure.  

Explain the role that body systems, organs, cells or tissues play in identity

Cells contain the DNA that codes for proteins

Explanation:

Water found in an river is...

A - Salt Water
B - Fresh Water

Answers

Answer:

B fresh water. salt water is a mixture found in oceans. hope this helps!

In your own words describe how genetic diversity is increased through the processes of crossing over, independent assortment, and random sexual reproduction.

Answers

Answer: Genetic variation describes naturally occurring genetic differences among individuals of the same species. Gene duplication, mutation, or other processes can produce new genes and alleles and increase genetic variation. New genetic variation can be created within generations in a population, so a population with rapid reproduction rates will probably have high genetic variation. And there are the reasons.

In the Calvin cycle the conversion of energy poor carbon dioxide into energy rich glucose

A) atp is used
B) pyruvic acid is produced
C) oxygen is produced
D) nadph is made

Answers

Answer:

D)NADPH is made

A)ATP is used

Explanation:

Sorry to ask the two questions, I asked why the two options are in the process:Reduction. In the second stage, ATP and NADPH are used to convert the 3-PGA molecules into three-carbon sugar molecules, glyceraldehyde-3-phosphate ( G3P ). At this stage, it gets its name because NADPH donates, or reduces , electrons to a three-carbon intermediate to form G3P.[Ocultar detalhes]

The reduction stage of the Calvin cycle, which needs ATP and NADPH, converts 3-PGA (produced in the fixation stage) into a three-carbon sugar. This process takes place in two main stages:

Simplified diagram of the reduction step of the Calvin cycle showing the carbon atoms, but not the complete molecular structures. A 3-PGA molecule first receives a second phosphate group from ATP (generating ADP). Then, the doubly phosphorylated molecule receives electrons from NADPH and is reduced to form glyceraldehyde-3-phosphate. This reaction generates NADP + and also releases an inorganic phosphate.

Simplified diagram of the reduction step of the Calvin cycle showing the carbon atoms, but not the complete molecular structures. A 3-PGA molecule first receives a second phosphate group from ATP (generating ADP). Then, the doubly phosphorylated molecule receives electrons from NADPH and is reduced to form glyceraldehyde-3-phosphate. This reaction generates NADP + and also releases an inorganic phosphate.

First, each 3-PGA molecule receives a phosphate group from ATP, becoming a doubly phosphorylated molecule called 1,3-bisphosphoglyceride (and leaving an ADP as a by-product).

Second, 1,3-bisphosphoglycerate molecules are reduced (gain electrons). Each molecule receives two electrons from NADPH and loses one of its phosphate groups, becoming a three-carbon sugar called glyceraldehyde-3-phosphate (G3P) . This step produces NADP^+

+

start superscript, plus, end superscript and phosphate (\text P_iP

i

start text, P, end text, start subscript, i, end subscript) as by-products.

The chemical structures and real reactions are:

Reactions of the Calvin cycle reduction step, showing the molecular structures of the molecules involved.

Reactions of the Calvin cycle reduction step, showing the molecular structures of the molecules involved.

The ATP and NADPH used in these steps are products of the photo-dependent reactions (first stage of photosynthesis). That is, the chemical energy of ATP and the reducing potential of NADPH, both produced with the use of light energy, keep the Calvin cycle running. Conversely, the Calvin cycle regenerates ADP and NADP^+

+

start superscript, plus, end superscript, providing the necessary substrates for photo-dependent reactions.

Answer:

m

Explanation:

m

21. A solution of pH 7.0 is_? Acidic Basic or Neutral

Answers

Answer:

Neutral

Explanation:

Less than 7 acidic

7 neutral

More than 7 basic

this life cycle is...
a. haplontic
b. diplontic
c. haplodiplontic

Answers

Answer:

C

Explanation:

a b c d ? anyone help pls

Answers

Answer:

Nucleus

Explanation:

It is the brain of the cell and controls and regulates the activities of the cell

Label the parts of the flower.

Answers

Answer:

A. Ovule

B. Ovary

C. Style

D. Stigma

E. pollen

F. Anther

G. sepal

H. fillamrnt

I. Sepal

J. Petal

Explanation:

bright

Answer:

the parts of the flower is listed above.

Which is a common use of minerals?

A.pasta
B.toothpaste
C.applesauce
D.wooden craft stick

Answers

Answer: Toothpaste!!

Explanation:

Toothpaste commonly uses minerals like calcium and fluoride etc.

Hope this helps!!! :D

Answer:

The answer is B. toothpaste.

Explanation:

This is because toothpaste contains minerals like fluorid, and sometimes charcoal. I really hope this helps! If your reading this right now I hope you get a good grade and god bless you, your family, and friends! Happy Thanksgiving!✨

Which molecule can freely diffuse through the cell membrane?

Oxygen

Nitrogen

Hydrogen

Glucose

Answers

nitrogen



explanation:
It would be nitrogen

Can someone help me with this

Answers

Answer:

true false true

Explanation:

I've done this before and got it right

True, False, True mark me brainliest I need to level up!!!

A mosquito larva diving away from the surface of the water when it sees a shadow would be an example of which characteristic of life?

Question 10 options:

homeostasis


responding to the environment


growth and development


reproduction

Answers

Answer:

responding to the environment...

Explanation:

Answer:

responding to environment

What do I say for these three questions?

Answers

Answer:

6. Amoxicillin & Metronidazle

7. Ibuprofen(acetaminophen) & (metformin) glucophage

8.1. Ibuprofen, tylenol, advil. 2. glucophage

Explanation:

1 . Amoxicillin and Merronidazle are 2 of the most used antibiotics. 2 Ibuprofen is medicine used for headaches, and metformin is normally related to sugar issues. 3. these are types of medicines that are from a certain generic name.

Cells for asexual reproduction is it mitosis or meiosis

Answers

Answer:

I believe it is mitosis.

Explanation:

I've made sure to check on google, mitosis is the splitting of a cell to create a second identical copy, this can be done asexually.

Hope this helps, if I was wrong please tell me.

There are _____ levels of intellectual disabilities on the modern continuum.

A.
five
B.
four
C.
three
D.
two

Answers

Answer:

B) Four

Explanation:

There are four levels of intellectual disabilities on the modern continuum. The correct option is B.

What are intellectual disabilities?

A person is said to have an intellectual disability when their capacity to learn at a typical rate and function in daily life is restricted. The severity of intellectual disability in children varies widely.

Despite the fact that a precise full-scale IQ test result is no longer necessary for diagnosis, standardised testing is nevertheless used to help make the diagnosis.

A full-scale IQ score of between 70 and 75 denotes a considerable intellectual functioning restriction.

Each person's level of difficulty with learning and processing information, difficulties with abstract cognition, and issues with social interaction are all common aspects of intellectual impairments.

On the contemporary continuum, there are four stages of intellectual disability.

Thus, the correct option is B.

For more details regarding intellectual disabilities, visit:

https://brainly.com/question/10554097

#SPJ6

Brainliest!!!!!
i dont understand this....

Answers

1. Trachea

2. Bronchi

3. Alveolar sacs

4. Capillaries

Hope this helps! :)

TRUE FALSE: Organisms can CHOOSE to have a mutation

Answers

Answer:

False

Explanation:

Organisms themselves cannot choose to have a mutation. However, it can be artificially done in labs.

Organisms can choose to have a mutation, but this is a false statement because mutation is not voluntary but involuntary and can be caused by many factors, such as environmental factors.

What is the significance of the mutation and its consequences?

mutation has many consequences, such as the Mutations can cause developmental disorders such as birth defects, mutations can increase an individual's risk of developing genetic disorders, and they also reduce the genetic diversity of a population. Mutation leads to the loss of function in an essential gene, resulting in a decrease in the organism's fitness in the ecosystem.

Hence, organisms can choose to have a mutation, but this is a false statement because mutation is not voluntary but involuntary and can be caused by many factors, such as environmental factors.

Learn more about the mutation here.

https://brainly.com/question/17130462

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The conversion of stored potential energy into kinetic energy can also be harnessed to power homes, factories and entire cities. Which example from the text supports this conclusion?

Answers

Answer:

The conversion of stored potential energy into kinetic energy can also be harnessed to power homes, factories and entire cities. The most notable example is the Hoover Dam. The Hoover Dam is an arch-gravity dam by design. This design name is the first clue as to how exactly the dam harnesses energy.

PLEASE HELP!!!!!!
The energy available at the trophic level that has producers is 1000 kilocalories. How much of this energy is most likely transferred to the trophic level that has primary consumers? A. 1 kilocalories B. 10 kilocalories C.100 kilocalories D. 1000 kilocalories

Answers

Answer:

C. 100 kilocalories

Explanation:

Only a little amount of energy as 10% is transferred to the next trophic level. This is called 10% rule.

Answer:

C

Explanation:

What does the SAGE instrument measure?

Answers

Answer:

The SAGE instrument measures the amount of ozone and other trace gases that are in the atmosphere by measuring the amount of sunlight that comes through the atmosphere at different altitudes.

Explanation:

What is differentiation in living things?

Answers

Cell differentiation: The development of cells in different ways to carry out specific human functions. This can cause specialized tissues. Often a group of cells specialize in the same way to carry out a certain function.
Cellular differentiation is the process in which a cell changes from one cell type to another. Usually, the cell changes to a more specialized type. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell.

PLEASE HELP!!!! 20 POINTS!!!!
Which event can cause slumps, landslides, and mudflows to occur?

earthquakes
hurricanes
snowfalls
thunderstorms

Answers

Answer:

earthquakes

Explanation:

Answer:

earthquakes

Explanation:

because it is muddy

brainliest - An offspring inherits an equal amount of its genetic information from each parent true false

Answers

Answer:

true

they get equal chromosome from each parent.

Answer: False

Explanation:

While women do inherit 50% of their DNA from each parent, men inherit about 51% from their mother and only 49% from their father. ... To answer this question, first a little 101 in genetics: all humans, both male and female, inherit 23 chromosome pairs from their parents, for a total of 46 chromosomes

Use the diagram to answer the question. Between which parts of the molecule must the bonds be broken to form an ADP molecule?

Answers

The parts of the molecule whose bond must be broken to form an ADP molecule would be between C and D. Thus, option A would be correct.

The image is an illustration of the structure of ATP, Adenosine Triphosphate. The hydrolysis of the terminal phosphoanhydridic bond in ATP yields energy for metabolic reactions in biological systems and ADP (Adenosine Diphosphate) is formed as a result.

In this case, the terminal phosphoanhydridic is D. Thus, the bond between D and C must be broken for ADP to result.

More on ATP hydrolysis can be found here: https://brainly.com/question/11813492

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