To create a dopamine deficient (dd) mouse that retains the ability to produce ne, the gene for dopamine beta-hydroxylase (DBH) is selectively restored in noradrenergic neurons.
DBH is an enzyme that converts dopamine to norepinephrine (ne), and its expression is critical for the production of ne. By restoring DBH expression specifically in noradrenergic neurons, researchers can create a mouse that lacks dopamine but still produces ne.
This can be a useful tool for studying the effects of dopamine deficiency on behavior, as well as the specific roles of dopamine and ne in various physiological processes. Additionally, this technique could potentially be used to develop new treatments for disorders that involve abnormalities in dopamine or ne signaling, such as Parkinson's disease or depression.
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using the chart below, explain which organism is most closely related to the human and why? which is most distantly related and why?
You can see from the chart below that the first species is in the animal kingdom while the other three are in the plant world. Just below the level of domains, the kingdom is a very high degree of categorization.
As a result, creatures from various kingdoms have relatively little in common. Sponge species are our most distant cousins according to the conventional animal tree of life. Like our non-animal ancestors (such as fungi), sponges are structurally basic creatures that lack many sophisticated animal characteristics including a nervous system, muscles, and a through-gut.
The gorillas, chimpanzees, and orangutans are the big apes that resemble humans the most physically. Yet, DNA testing has revealed that the chimpanzees are our closest living cousins; 95% of our DNA is the same.
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Using the chart below, explain which organism is most closely related to the human and why? which is most distantly related and why?
How does water flow?
A research team has genetically engineered a strain of fruit flies to eliminate errors during DNA replication. The team claims that this will eliminate genetic variation in the engineered flies. A second research team claims that eliminating errors during DNA replication will not entirely eliminate genetic variation in the engineered flies
(a)Provide ONE piece of evidence that would indicate new genetic variation has occurred in the engineered flies.
New phenotypes provides a piece of evidence that new genetic variation occurs in engineered fruit flies.
In genetics, a phenotype is a set of observable features or characteristics of an organism. The term covers an organism's morphology (physical form and structure), developmental processes, biochemical and physiological characteristics, behavior and products of behavior. The phenotype of an organism is produced by two fundamental factors: the expression of the organism's genetic code (its genotype) and the influence of environmental factors. These two factors may interact to further influence the phenotype. When two or more distinct phenotypes exist within the same population of a species, the species is said to be polymorphic.
A well-documented example of polymorphism is the color of the Labrador Retriever; while coat color depends on many genes, yellow, black, and brown can be clearly seen in the environment. In 1978 and again in his 1982 book The Extended Phenotype, Richard Dawkins proposed that bird's nests and other architectural structures such as stone silkworm larvae and beaver ponds) are considered as "extended phenotypes".
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