A Scientist discovers a chemical that she thinks might be a potential treatment for a certain type of cancer cell. In order to test her hypothesis, the scientist treats one plate of cancerous cells with the newly discovered chemical, and leaves another plate of cancerous cells untreated. After 7 days, the scientist measures the number of living cells in each plate. The scientist finds that the cells treated with the chemical have a lower survival rate than cells left untreated. The scientist further observes that the substance has an effect on the Rough endoplasmic reticulum (RER). How might disabling the rough ER potentially hurt the cancerous cells? Be specific in your answer. What is the dependent variable? What is the independent variable?

Answers

Answer 1

Answer:

Affecting the ER causes alteration in cell homeostasis and eventual death.Independent variable: Drug or chemicalDependent variable: Cancer cells survival.

Explanation:

Hypothesis ⇒ A chemical ⇒ might be a potential treatment for cancer cells.

Experiment:

Treated ⇒ One plate of cancerous cells with the new chemicalUntreated ⇒ Another plate of cancerous cells with no chemical

7 days later ⇒ the number of cells in each plate

Results:

Cells treated with the chemical have a lower survival rate than cells left untreated.

Treated plate ⇒ fewer cellsUntreated plate ⇒ more cells

Chemical affects the Rough endoplasmic reticulum (RER)

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The endoplasmic reticulum is in charge of many cellular functions, such as protein folding, maturation, and transport, especially those destined for secretion. It produces the latest protein modifications after transduction.

When the synthesizing protein gets in the Rough endoplasmic reticulum,  it continues its building in the organelle. Finally, the protein suffers folding and the initial stages of glycosylation.  

Once the protein synthesis in the endoplasmic reticulum is over, these molecules are packaged into vesicles and sent to the Golgi complex for their final association with carbohydrates. Finally, protein leaves the Golgi complex and goes to its final destiny.

Any alteration in the intracellular environment

inevitably affects the organelle and its functions. When the organelle is not properly working, proteins synthesis is affected and, consequently, all the cellular activities. The affected cell homeostasis might be so altered that the cell ends dying.

If the drug affects the ER by altering its environment or directly affecting it, the organelle will fail to perform its functions, and the cell will eventually dye.

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The independent and the dependent variables are the two principal factors needed in an experiment.  

 Independent variable: Refers to all the variables in an experiment that provoke a response in another variable. The independent variable changes or is controlled and modified in the experiment to analyze how another variable responds to it. It changes to analyze its effects on the dependent variable. Usually, the independent variable is represented by the X letter.

In the exposed example, the independent variable is the drug that affects the cancer cells. The researcher decides to apply it or not, and the concentrations in which the drug is.  

Dependent variable: Refers to the variable that reacts to the changes produced in the independent variable. Depending on how the independent variable is modified, the dependent variable change.  It is usually identified by the letter Y.

In the exposed example cell survival is the dependent variable. Cancer cells respond to the presence/absence of the chemical, and might differently respond to the varying concentration of the drug.


Related Questions

Science, Geology, Class 8

1. choose the correct answer ( CTCA )
a. what makes the soil fertile?
i. rock particles
ii. humus
iii. sand particles
iv. silt particles​

Answers

Answer:

Humus

Explanation:

Also known as the uppermost layer of soil, that's for making soil more fertile due to its organic content.

can you suggest me some biology experimental project work topics?​

Answers

Answers:

1. General

2. Reproduction

3. Health

4. Genetic Engineering

5. Technical Experiments on Humans

6. Relationships and Media

7. War

8. Information and Communication Tech

9. Computer Science and Robotics

One moth population carries three alleles at a genetic locus: X1, X2and X3. X1is dominant to X2and X3; X1produces red antennae. X2is co-dominant to X3; X2X2produces yellow antennae, X3X3produces white antennae, and X2X3produces light yellow antennae. The phenotypes in a population are as follows: 0.04 white; 0.16 light yellow; 0.16 yellow; 0.64 red.Assuming that this population is in Hardy-Weinberg equilibrium, what is the frequency of the X3allele in this population

Answers

Answer:

The correct answer is - 0.20

Explanation:

According to Hardy Weinberg equation under specific conditions the frequencies of the allele in the gene in a given population remain constant. Thus according to this frequencies of allele and genotype will remain the same through the generation unless there will be no evolutionary influence.

It helps us to predict the genotype frequencies in a large population.  If there are two alleles having allelic frequencies p and q and we know equation of probability and frequencies add to 1

p2+2pq+q2=1

The X3X3 genome produces white antennae. Now Phenotypic frequency of the white antennae is 0.16 or 0.04 in the whole population. Hence the frequency of X3 should be a square root of 0.04 i.e, 0.20.

Some birds on the Galapagos Islands build nests in trees, while others hide eggs in rock crevices. What could account for this difference in nesting behaviors?

Answers

Answer:

Food habits, predators.

Explanation:

The biggest reasons are food habits and predators, most birds who nest on the ground either can't fly or use this to be closer to their food. A ground bird (Like quail) can fly but choose to be more ground-based birds.

Most of the time it's because these birds forage for food like ground insects, seeds from the brush that grows on the ground, or fallen fruit.

Most birds that live in the trees feast on seeds, leaves, or insects found close to where they choose to nest. They may also want to escape any predators that may be towards the ground.

Which of the following statements about cardiac muscle is true? a. Cardiac muscle is like smooth muscle, because smooth muscle has a banded appearance. b. Cardiac muscle is like smooth muscle, because it contains no bands. c. Cardiac muscle contains bands like skeletal muscle, but its contractions are involuntary like smooth muscle. d. Cardiac muscle is like skeletal muscle, because skeletal muscle has involuntary contractions.

Answers

Answer:

c. Cardiac muscle contains bands like skeletal muscle, but its contractions are involuntary like smooth muscle.

Explanation:

In Human anatomy, cardiac cycle can be defined as a complete heartbeat of the human heart which comprises of sequential alternating contraction and relaxation of the atria and ventricles, therefore causing blood to flow unidirectionally (one direction) throughout the human body.

Cardiac muscle is also referred to as myocardium and it's one of the three (3) muscles found only in the heart of vertebrates, the other two (2) being smooth muscle tissue and skeletal muscle tissue.

Cardiac muscle contains bands like skeletal muscle referred to as sarcomeres (contractile units), but its contractions are involuntary like smooth muscle and it's typically being regulated by the sinoatrial node of the heart.

Why do doctors have to check what blood type a person has before receiving a
transfusion?
0
A. Different blood types have different antibodies that will be attacked by someone with
antigens against that blood type.
B. Different blood types have different antigens that will be attacked by someone with
antibodies against that blood type.
C. Your blood type doesn't matter as long as you get the correct amount of blood in a
transfusion.
O
D. They need to have the same blood type because their DNA must be similar enough to
blend or will cause side-effects and possibly be rejected.

Answers

Answer:

A. Different blood types have different antibodies that will be attacked by someone with

antigens against that blood type.

what is the purpose of ethical guidelines for the handling of experimental subjects

Answers

Answer:

The purpose of ethical guidelines for handling of experimental subjects is to ensure the safety and well-being of all living creatures in an experiment. Ethical guidelines include issues such as human rights, animal welfare, safety compliance with the law, conflicts of interest, health standards.

I have to write a hypothesis based on if plants need sunlight
I would put one plant inside and one outside with everything they get the same except the amount of sunlight

Answers

Answer:

Sunlight is related to plant growth. If the amount of sunlight is increased, then plant growth will increase. The hypothesis that plant growth increases as the amount of sunlight increases was supported by the data.

una persona camina durante una hora y media y corre 4 km con velocidad constante ¿cuál era su velocidad en km/h y en m/s?​

Answers

La respuesta es: su velocidad es 2.66 km/h, equivalente a 0.738 m/s.

Explanation

Para conocer la velocidad de una persona que recorrió 4 km luego de caminar durante una hora y media es necesario dividir la distancia (en kilómetros) total en el tiempo (en horas). Entonces la operación sería:

4km/1,5h = 2.66 km/h.

Posteriormente, para convertir 2.66 km/h en m/s es necesario aplicar la siguiente formula

2.66 km/h *(1000 m/1 km)*(1 h/3.600 s) = 0.738 m/s.

Which of the following is the only one that could cause a theory to change over time?
Group of answer choices

The discovery of new evidence

Exciting new—but untested--hypotheses

A series of new laws passed by the government

A change in public opinion

Answers

Answer:

may be

the discovery of new evidence

Explanation:

Accepted theories may be modified or overturned as new evidence and perspective emerges. Scientists are likely to accept a new or modified theory if it explains everything the old theory did and more. The process of theory change may take time and involve controversy, but eventually the scientific explanation that is more accurate will be accepted.

A millimeter, a meter, and a kilometer are all measures of distance. What is
another way to classify them?
O A. U.S. customary units
B. Measures of mass
C. Measures of volume
D. Metric units

Answers

Answer:

I think the correct answer is D

Traits can also be
, which means they can be masked

Answers

Answer:

is that a question?

Explanation:

What is the independent and dependent variable? Two groups of students were tested to compare their speed working math problems. Each group was given the same problems. One group used calculators and the other group computed without calculators
__________________________

Answers

Answer:

The dependent variable is the one that depends on the value of some other number. ... Another way to put it is the dependent variable is the output value and the independent variable is the input value. So for y=x+3, when you input x=2, the output is y = 5.

Hope this helps you ❤️

MaRk mE aS braiNliest ❤️

What does the word Photosynthesis mean?
A. Release of energy through the breakdown of Glucose.
B. Creating photographs.
C. Taking apart with light.
D. Putting together with light.

Answers

Answer:

A

Explanation:

release of energy through the breakdown of glucose

The release of energy through the breakdown of Glucose means Photosynthesis.

Photosynthesis

Photosynthesis is a process used by plants and other organisms to convert light energy into chemical energy that, through cellular respiration, can later be released to fuel the organism's activities. Some of this chemical energy is stored in carbohydrate molecules, such as sugars and starches, which are synthesized from carbon dioxide and water – hence the name photosynthesis, from the Greek phōs  "light", and synthesis  "putting together" Most plants, algae, and cyanobacteria perform photosynthesis; such organisms are called photoautotrophs. Photosynthesis is largely responsible for producing and maintaining the oxygen content of the Earth's atmosphere and supplies most of the energy necessary for life on Earth.

Although photosynthesis is performed differently by different species, the process always begins when energy from light is absorbed by proteins called reaction centers that contain green chlorophyll (and other colored) pigments/chromophores. In plants, these proteins are held inside organelles called chloroplasts, which are most abundant in leaf cells, while in bacteria they are embedded in the plasma membrane. In these light-dependent reactions, some energy is used to strip electrons from suitable substances, such as water, producing oxygen gas.

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Question 17 of 25
Why do plants produce more carbon dioxide than oxygen during the night?
O A. Respiration produces oxygen during the day and carbon dioxide at
night.
B. Respiration can happen without sunlight, but photosynthesis
cannot.
O C. Respiration can only occur when there is no available sunlight.
O D. Photosynthesis only produces carbon dioxide during the night.
SUBMIT

Answers

Answer:

B

Explanation:

Respiration can happen without sunlight,but photosynthesis cannot.and photosynthesis doesn't take place at night,so less carbon dioxide is used up than it is produced.

I hope this helps

You have been asked to help a top nutrition researcher conduct human experiments on vitamin C. As the subjects walk into the laboratory, you distribute all the vitamin C pill bottles to the girls and all the placebo pill bottles to the boys. The researcher instantly informs you that there are two errors in your research practice. What steps should you have done differently?
a. given all the boys the vitamin C and the girls the placebo, and told them what they were getting
b. Distributed the bottles randomly, randomized the subjects, and told them what they were getting.
c. Told the subjects which group they were in, and prevented yourself from knowing the contents of the pill bottles.
d. Prevented yourself from knowing what was in the pill bottles, and distributed the bottles randomly to the subjects.

Answers

Answer:

Option D

Explanation:

Prevented yourself from knowing what was in the pill bottles, and distributed the bottles randomly to the subjects.

Which of the following workers is a maintenance staff member?

Answers

E because his job is what the question describes

Fill in the blanks:
In water and ice, the slightly ______ hydrogen atoms in one water molecule are drawn to the slightly _______ oxygen atom in another water molecule.

A. positive, negative

B. negative, positive

C. neutral, positive

D. neutral, negative

Answers

Answer:

option c

Explanation:

The water molecule is a polar substance that has partially charged ions. The hydrogen atom is partially positive, whereas the oxygen atom is partially negative in charge. Thus, option A is correct.

What is polarity?

The polarity of the molecule is defined by the presence of the electrical charges over the elemental atom that results in the formation of the chemical bonds by the electrostatic forces.

Water is an example of a polar molecule that is linked by a covalent bond by sharing the electrons between the oxygen and the hydrogen atom of the molecule.

The hydrogen atom is said to have a partial positive charge and oxygen has a partial negative charge because of the uneven electron density. The electronegative oxygen pulls the hydrogen towards it.

Therefore, option A. hydrogen is partially positive and oxygen is partially negative.

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Which is the best interpretation of the two flat portions of the graph?

A. These show where the temperature is 0ºC.

B. These show where changes of state are occurring.

C. These show where kinetic energy is increasing.

D. These show where thermal energy does not exist.

Answers

Answer:

B, they are changes of state.

The best interpretation of the two flat portions of the graph where these shows that change of state are occurring. Thus, C is correct option.

What are change of state?

A state is physical condition of any substances it means that any substance which found on earth are mainly found in three states and these are following:-

1- Solid

2- Liquid

3- Gas

A change of state is physical change of state i.e any substance which changes their state from ( solid to liquid called melting), (liquid to gas called evaporation), (gas to solid called diffusion) etc  are called change of state.

These change of state occurs when temperatures or pressure changes in a system or substances. When the temperature or pressure increase  the interaction between the molecules also increases.

Therefore,the best interpretation of the two flat portions of the graph where these shows that change of state are occurring. Thus, C is correct option.

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Carbohydrates info
A. AKA:
B. Composed of:
C. Monomer:
D. Polymer:
E. Functions:

Answers

A: Carbs
B:Carbon, hydrogen and oxygen
C:Monosaccharides
D:Polysaccharides
E: Provides energy to the human body.

Look at the branching tree diagram below.

A slanting, horizontal line is shown. On the extreme left, there is a label that says Common Ancestor. Along the slanting, horizontal line there are five dots labeled from left to right with the following traits Four limbs, Amniotic egg, Fur, Shearing teeth, and Retractable claws. There is one vertical line between each of the consecutive five dots. The lines are labeled from left to right as Amphibians, Reptiles, Marsupials, Dogs, Cats.

Which group of organisms evolved after dogs?

Only cats
Only marsupials
Both cats and marsupials
Both amphibians and reptiles

Answers

Answer:

both cats and marsupials

Answer:   Both Amphibians and Reptiles

Explanation: I took the test and got it, so.....

What are three blood cells in a human body

Answers

Answer:

red

white

platelets

Explanation:

these are the three blood cells in the human body

red white and platelets

Explain how various animal species have rapidly evolved as a result of human impact.

Answers

Answer:

Numerous examples of this human-induced contemporary evolution have been reported in a number of 'contexts', including hunting, harvesting, fishing, agriculture, medicine, climate change, pollution, eutrophication, urbanization, habitat fragmentation, biological invasions and emerging/disappearing diseases.

Explanation:

Approximately how many mutations occur naturally in DNA per 10,000 bases?
A. 2
B. 2000
C. 200
D. 20

Answers

Explanation:

Modern methods indicate that the mutation rate is roughly one to two mutation per 10,000 genes per generation.

In human cells, approximately TWO (2) MUTATIONS occur naturally in DNA per 10,000 bases (Option A is correct).

The mutation rate (u) refers to the occurrence of new mutations in a given nucleotide sequence over time.

In human cells, the mutation rate is approximately 10⁻⁴ per generation.

Therefore, in a DNA sequence that has 10,000 base pairs of length, this value is equal to 2 mutations per generation (u = 2 / 10,000 = 10⁻⁴).  

In conclusion, approximately 2 MUTATIONS occur naturally in DNA per 10,000 bases (Option A is correct).

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What is a genotype???????

Answers

Answer: A genotype is an individual's collection of genes.

Explanation:

All enzymes which catalyze the chemical reactions of a cell are
a. carbohydrates b. lipids c. long-chain fatty acids d. proteins e. ribonucleic acids no another by differences in​

Answers

Answer:

I think the answer will be protein.

Answer:

the answer is carbohydrates

The human heart weighs how many pounds

Answers

After careful consideration your answer is...

Just about 1 pound

*Hope I helped*

~Alanna~

1 lb (pound)

Explanation:

it is the answer.

Which type of plate boundary would be most likely to lead to above-ground volcanic activity?

A . Subduction
B .divergent
C.collisional
D . Transform

Answers

Answer:

A.Subduction

Explanation:

In a subduction zone, one plate slides beneath another. This leads to friction that can melt the crust and result in volcanic activity

what is the average lifespan of a sperm cell​

Answers

[tex]Hello[/tex] [tex]There![/tex]

The answer is...

5 days at least.

Good luck!

[tex]AnimeVines[/tex]

Explanation:

the answer is up to 5 days

state te type of cell devision of cross section tips of onion root.​

Answers

mitosis and/or meiosis is the anwser
Other Questions
Drag the tiles to the correct boxes to complete the pairs. Not all tiles will be used. Match the systems of equations to their solutions. Questions 23 and 29: Use the following information to answer each question. A recent book noted that only 20% of all investment managers outperform the Dow Jones Industrial Average over a five-year period. A random sample of 200 investment managers that had graduated from one of the top ten business programs in the country were followed over a five-year period. Fifty of these outperformed the Dow Jones Industrial Average. Let p be the true proportion of investment managers who graduated from one of the top ten business programs who outperformed the Dow Jones over a five-year period. 23. Based on the results of the sample, a 95% confidence interval for p is: a. (1.95, 3.15) b. (0.0195, 0 .0315) c. (0.190, 0.310) d. (0.028, 0.031) e. (0.195, 0.315) f. We can assert that p = 0.20 with 100% confidence, because only 20% of investment managers outperform the standard indexes. 24. Suppose you had been in charge of designing the study. What sample size would be needed to construct a margin of error of 2% with 95% confidence? Use the prior estimate of p=0.2 for this estimate. a. n=2401 b. n=1537 c. n=16 d. n=1801 e. n>30 Suppose you wish to see if there is evidence that graduates of one of the top ten business programs performs better than other investment managers. Conduct a hypothesis test. Use a level of significance of =0.05 25. Which of the following pairs of hypotheses is the most appropriate for addressing this question? a. H0: p=0.2 Ha: p0.2 d. H0: p0.2 Ha: p=0.2 26. How many measurements must you have in order to assure that p^ is normally distributed? a. n30 b. n5 c. np10 and n(1p)10 d. np5 and n(1p)5 27. The value of your test statistic is: a. 1.768 b. 0.039 c. 1.923 d. 0.077 28. The P-value of your test is: a. 1.768 b. 0.039 c. 1.923 d. 0.077 29. Is there sufficient evidence to conclude that graduates from the top ten business programs perform better than other investment managers? a. Yes. I rejected H0 b. Yes. I failed to reject H0 c. Yes. I accepted Ha d. No. I rejected H0 e. No. I failed to reject H0 f. No. I failed to accept Ha nWhy might buying a home during a recession be a good decision for some consumers? Check all that apply.Housing pricegare down.It is easier to get a mortgage.Less demand means more options for buyers.Less demand means less competition with other buyers.Fewer houses are on the market. Debbie promises to sell Brian a one of a kind baseball card for $1,000. Brian says that he does not have the money right now, but will have at it his next paycheck. Debbie gives Brian a signed written notice that the offer will stay open for two months. Does it the analysis change if Debbie is a merchant seller for this to be a firm offer under the UCC?a. Yes, such offers are not reasonable.b. Yes, such offers are voidable.c. Yes, such offers are void.d. Yes, the offeror must be a merchant, pursuant to the UCC definition of merchant.e. Yes, such offers are only valid until the sun sets. An automobile assembly plant in Kentucky purchases several thousand unassembled parts for automobiles and then performs final assembly of the vehicles before delivering them to dealers all over the nation. Purchasing parts several days or weeks before they are assembled would increase the total cash outlay the plant has tied up in inventory at any given time. In order to reduce the expense of large inventories, most assembly plants have successfully adopted __________ inventory systems. Complete each sentence.a. Cross-bridge binding triggers the release of ATP hydrolysis products from _________, and produces the _______ which generates force. b. 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Explain why the balls representing fluorine (teal) and hydrogen (white) have only one peg, while carbon (black) has four. Can a man ejaculate by massaging the prostate gland manually? Does this result in an erection/orgasm? How would you be able to immediately tell whether a shale parent rock had been subjected to either intermediate-grade contact metamorphism or intermediate-grade mountain belt (regional) metamorphism? can books and stories about characters and event that are not real teach us anything useful How many alkenes are formed by E2 elimination of HBr from 3-bromo -3,4-dimethylhexane using a strong base such as sodium methoxide (NOTE: draw 3,4-dimethyl as anti configuration) a. Draw 2,3-dichloro octane.b. Write the lewis structure for H20 molecule. Filer Manufacturing has 8,136,353 shares of common stock outstanding. The current share price is $26.75, and the book value per share is $5.85. Filer Manufacturing also has two bond issues outstanding. The first bond issue has a face value of $48,480,532, has a 0.05 coupon, matures in 10 years and sells for 83 percent of par. The second issue has a face value of $66,060,894, has a 0.06 coupon, matures in 20 years, and sells for 92 percent of par. The most recent dividend was $1.97 and the dividend growth rate is 0.04. Assume that the overall cost of debt is the weighted average of that implied by the two outstanding debt issues. Both bonds make semiannual payments. The tax rate is 0.26. What is Filer's aftertax cost of debt? Enter the answer with 4 decimals (e.g. 0.2345) Consider these versions of The War of the Worlds.Excerpt 1, from H. G. Wells's novel The War of the Worlds:The common round the sand pits was dotted with people, standing like myself in a half-fascinated terror, staring at these creatures, or rather at the heaped gravel at the edge of the pit in which they lay. And then, with a renewed horror, I saw a round, black object bobbing up and down on the edge of the pit. It was the head of the shopman who had fallen in, but showing as a little black object against the hot western sun. Now he got his shoulder and knee up, and again he seemed to slip back until only his head was visible. Suddenly he vanished, and I could have fancied a faint shriek had reached me.Excerpt 2, from Howard E. Koch's script for Orson Welles's radio adaptation:PHILLIPS: Ladies and gentlemen, you've just heard Mr. Wilmuth, owner of the farm where this thing has fallen. I wish I could convey the atmosphere . . . the background of this . . . fantastic scene. Hundreds of cars are parked in a field in back of us. Police are trying to rope off the roadway leading to the farm. But it's no use. They're breaking right through. Cars' headlights throw an enormous spot on the pit where the object's half buried. Some of the more daring souls are now venturing near the edge. Their silhouettes stand out against the metal sheen.Which statement best describes the similarity between these versions?Both versions impart an urgent tone through a residents words.Both versions impart setting details through colorful description.Both versions explain the background of a scientific phenomenon.Both versions use characterization to show the locals' intelligence. What must you do to become ASE certified as an automotive technician? Describe these findings, and explaine their significants; epicanthal fold; pseudostrabismus; ophthalmia neonatorum; Brushfield spots. in what way do you think overseas commitment " influence the rise and fall of nations in Europe Find the median: 16.12.7.9.10.16