which of the following pharmacologic features is shared by all of the medications that have received fda approval for maintenance treatment of opioid use disorder?
A. FDA approved medications for maintenance or detoxification
B. Medications in schedules III, IV, or V
C. Buprenorphine or Buprenorphine/naloxone
D. Methadone

Answers

Answer 1

The pharmacologic feature shared by all of the medications that have received FDA approval for maintenance treatment of opioid use disorder is the use of agonist or partial agonist medications.

The medications that have received FDA approval for maintenance treatment of opioid use disorder are buprenorphine, methadone, and naltrexone. The medications that are shared by all of these medications are the use of agonist or partial agonist medications. Agents that activate the μ-opioid receptor and/or κ-opioid receptor partially or completely are known as agonist or partial agonist medications. Buprenorphine and methadone are agonist or partial agonist medications that activate the μ-opioid receptor completely. They both have a long half-life and may be taken once a day. Naltrexone is a pure antagonist that functions by blocking the effects of opioid agonists .Therefore, the correct answer is A. FDA approved medications for maintenance or detoxification.

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