What are the features of Nuclear Receptor Screening Services?

Nuclear receptors (NRs) are a class of proteins responsible for thyroid hormones and sensing steroid and certain other molecules. There are 48 genes in the human genome that code for the NRs. As the largest family of eukaryotic transcription factors, NRs control numerous processes involved in development, cell cycle, and important metabolic pathways.

https://dda.creative-bioarray.com/nuclear-receptor-screening.html

Answers

Answer 1

Answer:

The nuclear receptor superfamily comprises a large group of transcription factors that play a key regulatory role in development and homeostasis of multicellular organisms. A special feature of nuclear receptors is their ability to bind to condensed chromatin templates, which makes them important initiators of gene transcription. Moreover, the ability of nuclear receptors to sequentially recruit a variety of transcription factors and coregulators to target promoters and to orchestrate the whole process of gene transcription confirms their biological significance and stimulates intensive research and a high level of scientific interest in this field. In this review, we summarise current knowledge regarding the structure and function of nuclear receptors as principal regulators of gene expression. Emphasis is given to the molecular mechanisms of nuclear receptor-mediated transcriptional activation and repression including recent progress made in this area.


Related Questions

A microbiologist is conducting a research project on chemolithoautotrophs. This means that the investigator is examining certain aspects of a bacterium that is a purple nonsulfur bacteria which depends on light. uses light as its energy source and carbon for organic compounds. can oxidize inorganic molecules such as ammonia and sulfur for energy. can use the energy from sunlight to build organic molecules from carbon dioxide. obtains carbon from organic molecules.

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Answer:

uses light as its energy source and carbon for organic compounds.

Explanation:

The purple non-sulfur bacteria which depends on light produces organic food  just like plants through the process of photosynthesis. The purple non-sulfur bacteria uses carbondioxide and water with sunlight produces oxygen and glucose which is an organic compound. So that's why purple non-sulfur bacteria is also known as phototrophic means organism that produces their own food through photosynthesis.

1. The structure that's not a component of wall of sponges is

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Answer:

Chitin.

Explanation:

The structure that is not a component of wall of sponges is Chitin. Their body comprise of calcareous or siliceous spicules or protein spongin fibres. Choanocytes are the distinctive cells located in the interior body walls of sponges. Sponges are similar to other animals in many characteristics such as they are multicellular, heterotrophic, lack cell walls and produce sperm cells in order to produce offspring sexually and also different from animals due to lack of tissues and organs.

Explain the role of cellular respiration in a cell.

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Answer:

Every cell performs a type of cellular respiration as it is required to produce energy. The point of cellular respiration is to turn high-energy molecules, know as glucose, into ATP, a form of usable energy. There are two types of respiration, aerobic and anaerobic. Aerobic goes through 3 stages and produces the most ATP by using oxygen and releasing carbon dioxide. Anaerobic does the same job but only uses one stage and produces much less ATP. This process gives the cell energy and continues the carbon cycle.

Which critter trait is affected by an environmental factor, such as light, temperature, or
diet? Explain.

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Answer:

Tallness.

Explanation:

Tallness is the critter trait that is affected by an environmental factor, such as light, temperature, or  diet because the organism remains short if they are not getting food properly as well as temperature. Food provides essential nutrients that contribute in the growth of organism. Suitable temperature of the body allows the different functions in the body to be done which directly affects the growth of the body and the organism becomes taller.

Mode of action of aldehydes and Quaternary ammonium compounds is

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Answer:

Aldehydes have antibacterial, antifungal, antiviral and sporicidal activity. These are helpful to destroy the spores of Bacillus subtilis and Clostridium sporogenes. Glutaraldehyde and formaldehyde are commonly used aldehydes in disinfectants.

Quaternary ammonium compounds work by denaturing the proteins of the bacterial or fungal cell, affecting the metabolic reactions of the cell and causing vital substances to leak out of the cell, causing death.

Every day we make choices that can potentially affect our environment. For example, we may toss a plastic drink bottle into the nearby trash because it’s more convenient than walking all the way to the recycling bin. Think about three choices you made this week that could have affected the environment. Did your choices have a positive or a negative effect on the environment? Explain your reasoning.

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First, I chose to put a Chipotle container into the trash, instead of the recycling. This wasn’t the best decision, because it could have gone to the recycling and helped others.

Secondly, my family owns a compost bin and compost machine that helps compost vegetable waste, fruit scraps, coffee grounds, and other compostable items. Choosing to do this helps the environment in many ways.

Thirdly, I picked up many aluminum cans on the side of the road to crush and collect. After several months of collecting them in a container, my family and I bring them to a place that recycles and reuses metals and aluminum.

The three choices that could have affected the environment are as follows:

Utilization of plastic to make it easy for carrying objects.Plants trees in order to build a green environment. Overdependency on vehicles rather bicycles and pedestrians.

What is Environment?

The environment may be defined as anything which is present in the surroundings of living organisms. This environment basically has two types of factors biotic and abiotic factors.

In the above three choices, building a green environment has a positive effect on the environment. It may also affect living organisms positively. While the rest of the two may stimulate a negative impact on the environment by increasing the levels of carbon dioxide by liberating emission and non-biodegradable plastics.

Therefore, the three choices that could have affected the environment are well mentioned above.

To learn more about Environment, refer to the link:

https://brainly.com/question/24182291

#SPJ2

state economic importance of anaerobic respiration in plants​

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Answer:

Anaerobic respiration is economically significant since many of our meals are generated by anaerobic bacteria. To ensure its survival, the yeast must convert to anaerobic respiration. Carbon dioxide and ethanol are generated. Bread may also be made with yeast.

OAmalOHopeO

Which of these organelles prepares proteins to be fully functional?

A. Rough endoplasmic reticulum

B. Large vacuoles

C. Smooth endoplasmic reticulum

D. Chloroplasts

Answers

Rough endoplasmic reticulum

Answer:

Rough endoplasmic reticulum is among the organelles that are found in eukaryotic cells. The reason as to why it is called rough is because it has ribosomes attached to its surface. Its main function is to produce proteins.

Explanation:

I need to know which ones to check off

Answers

The instructions don’t really count toward your grade, if you really wish to learn from then you should just try your best and take notes on what you beed to know. If you’re just using Brainly to get past the class just guess on the instructions as they do not effect your grade very much at all if at all.

What is pasteurization? what is the advantage of this technique?

GIVE ANSWER IN POINTS
CLASS 8 ​

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Answer:

Pasteurization is the process by which food products (such as juice and dairy products) are mildly heated to kill off harmful bacteria, salmonella, and other disease-causing pathogens. These products are thus made safe for consumption. ... Pasteurization has revolutionized food safety within the dairy industry.

Identify the molecule that is not a compound

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Answer:

dear, your question seems to be incomplete.......plz ask it again

This could be Hydrogen gas as it is a molecule but is not a compound as it is only made up of one element!

The orbit radius of Uranus is 19.22 AU. What is this distance in kilometers? ( one au is about 150 million kilometers.)

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Answer:

2,883,000,000km

Explanation:

19.22*150,000,000km=2,883,000,000km

Describes vitamin D levels and problems

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Answer:

Vitamin D is essential for strong bones,because it helps the body use calcium from the diet.

It’s important for normal growth and development of teeth and bones. It can help resist against certain diseases. Some problems if you take to much vitamin D is that you will get weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, nausea, vomiting, and others.

What is limiting factor

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Answer:

limiting factors are often referred as a lack of a particular resource .

You have a microorganism you know is both fastidious and which normally lives in human lungs. Which medium might this organism have the highest probability of growing on and why

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Answer:

It is likely that this microorganism grows in enriched culture media.

Explanation:

As shown in the question above, the microorganism that lives in the lungs is extremely demanding. This means that this microorganism is very difficult to be cultivated in a culture medium, as it requires specific nutrients and in specific amounts to be able to develop. These microorganisms are called fastidious microorganisms and need an enriched culture medium to develop.

Enriched culture media are those that have a high range of nutrients in their composition. These culture media are highly nutritious and for this reason, they are the ideal environment for demanding microorganisms, as it can efficiently meet the needs of this organism.

In which of the scientific classifications are all the
animals grouped

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The lion belongs to the following groups: Kingdom Animalia (includes all animals) Phylum Chordata (includes all vertebrate animals, as well as some other more primitive ones) Class Mammalia (includes all mammals)

which photo synthetic process can occur at night?
A.the reaction at photosystem 1
B.the formation of NADH
C.the calvin cycle
D.the reaction at photosystem 2

Answers

Its most likely D because it’s more reasonable

Organisms are either eukaryotes or prokaryotes. Prokaryotes are further classified into the domains Archaea or Bacteria, while all eukaryotes are in the domain Eukarya.

a. True
b. False

Answers

Answer:

This is true

Explanation:

Suppose beak size currently ranges from 6-10mm. If directional selection favors larger beaks (up to a max of 15mm), which statement is true?

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source of variation needs to create that size

What is a controlled variable?

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Answer:  A controlled variable or constant variable is a variable that does not change during an experiment.

Explanation:

A controlled variable or constant variable is one which the researcher holds constant (controls) during an experiment. It is also known as a constant variable or simply as a control.The control variable is not part of an experiment itself it is neither the independent nor dependent variable but it is important because it can have an effect on the results gotten.

example of a controlled variable is temperature.

A certain animal species has either curly tails (C) or straight tails (c) and either hazel eyes (H) or blue eyes ( h). What are the possible genotypes of an animal with curly tails and blue eyes

Answers

Answer:

CChh

Cchh

Explanation:

Cc or CC can be a genotype for curly tails because both have a dominant allele for curly tails

hh can be a genotype for blue eyes because there are two recessive alleles for blue eyes that are present

hi,I was feeling so bored so I give this question What is climate change and what r the causes of climate change?​

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Answer:

Climate change is the global phenomenon of climate transformation characterized by the changes in the usual climate of the planet (regarding temperature, precipitation, and wind) that are especially caused by human activities

Humans are increasingly influencing the climate and the earth's temperature by burning fossil fuels, cutting down forests and farming livestock. This adds enormous amounts of greenhouse gases to those naturally occurring in the atmosphere, increasing the greenhouse effect and global warming. Humanity’s increased use of fossil fuels – such as coal, oil and gas to generate electricity, run cars and other forms of transport, and power manufacturing and industry

Deforestation – because living trees absorb and store carbon dioxide

Increasingly intensive agriculture – which emits greenhouse gases like methane and nitrous oxide

The most direct method by which an ion or molecule can move across a cell membrane is by ____________.A. using an integral protein.B. a sodium-potassium pump.C. simple diffusion. D. active transport.E. osmosis.

Answers

Answer:

C. Simple diffusion

Explanation:

Simple diffusion from a high to low concentration is the most direct method that ions or molecules can move across a cell membrane.

Through this method, no proteins are required for transport, and no energy is used.

The ion or molecule being transported directly moves across the cell membrane, without any other factors involved.

So, the correct answer is C. Simple diffusion

PNS axons are vulnerable to cuts, crushing injuries, and other types of trauma. However, a damaged ____________ can regenerate if the ____________ remains intact and a critical amount of ____________ remains. The success of peripheral nervous system axon regeneration depends upon two primary factors: (1) the amount of ____________ and (2) the ____________ between the site of the damaged axon and the ____________ . The possibility of repair is ____________ with an increase in either of these two factors. Neurolemmocytes play an active role in regeneration

Answers

Answer:

The correct answer is - damaged, effector organ, neurilemma, damage, distance, cell body, decreased.

Explanation:

PNS axons are prone to cuts, and other types of injuries. A damaged axon can regenerate if the effector organ remains intact and a critical amount of neurilemma is found.

The degree of success of these axons regeneration depends upon factors that are (1) the amount of damage, and (2) the distance between the site of the damaged axon and the cell body it innervates The possibility of repair is reduced with an increase in either of these two factors. Neurolemmocytes play an active role in regeneration

Câu 4: Nghiên cứu về lạm phát nằm trong đối tượng của…
a. kinh tế học vi mô.
b. kinh tế học vĩ mô.
c. kinh tế học thực chứng.
d. kinh tế học chuẩn tắc.

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Answer:

Explanation:

B. Kinh tế học vĩ mô

Tell me how bacteria make their energy and other chemical products.

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Answer:

Bacteria can obtain energy and nutrients by performing photosynthesis, decomposing dead organisms and wastes, or breaking down chemical compounds. Bacteria can obtain energy and nutrients by establishing close relationships with other organisms, including mutualistic and parasitic relationships.

Explanation:

I hope it helps! Please mark my answer as bräinliest! Thank You!

Based on the Punnett square above, what are the genotypic and phenotypic ratios of the offspring? A red plant and a pink plant. Red plant genotype: Pink plant genotype: Phenotypic ratio: Red = Pink = White = Genotypic ratio: RR = Rr = rr =

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Answer:

GivEn:

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The ratio of two sides of a parallelogram is 2 : 5.Perimeter of parallelogram = 70 cm

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To find:

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Sides of parallelogram?

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Solution:

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☯ Let two adjacent sides of parallelogram be 2x and 5x.

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Refrence of image is shown in diagram:

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[tex]\setlength{\unitlength}{1 cm}\begin{picture}(0,0)\thicklines\qbezier(1,1)(1,1)(6,1)\put(0.4,0.5){\bf D}\qbezier(1,1)(1,1)(1.6,4)\put(6.2,0.5){\bf C}\qbezier(1.6,4)(1.6,4)(6.6,4)\put(1,4){\bf A}\qbezier(6,1)(6,1)(6.6,4)\put(6.9,3.8){\bf B}\put(0.7,2.5){\sf 2x}\put(3,0.5){\sf 5x}\end{picture}[/tex]

⠀⠀⠀⠀⠀⠀⠀

[tex]\underline{\bigstar\:\boldsymbol{According\:to\:the\:question\::}}\\ \\[/tex]

Perimeter of parallelogram = 70 cm

⠀⠀⠀⠀⠀⠀⠀

[tex]\dag\;{\underline{\frak{We\;know\;that,}}}\\ \\[/tex]

[tex]\star\:{\boxed{\sf{\purple{Perimeter_{\;(parallelogram)} = 2 \times (sum\:of\: adjacent\:sides)}}}}\\ \\[/tex]

[tex]:\implies\sf 2 \times (2x + 5x) = 70\\ \\[/tex]

[tex]:\implies\sf 2 \times 7x = 70\\ \\[/tex]

[tex]:\implies\sf 14x = 70\\ \\[/tex]

[tex]:\implies\sf x = \cancel{ \dfrac{70}{14}}\\ \\[/tex]

[tex]:\implies{\boxed{\sf{\pink{x = 5}}}}\;\bigstar\\ \\[/tex]

Therefore,

⠀⠀⠀⠀⠀⠀⠀

2x = 2 × 5 = 10 cm.

5x = 5 × 5 = 25 cm.

⠀⠀⠀⠀⠀⠀⠀

[tex]\therefore[/tex] Hence, Adjacent sides of parallelogram are 10 cm and 25 cm.

In general, men show _____ than women do. a. less facial expression b. more facial expression c. less envy or anger d. more envy or anger

Answers

Answer:

more envy and anger

Explanation: they cant control themselves lol.

Table sugar is an example of which molecule

Answers

Answer:

Disaccharide

Explanation:

It is a disaccharide, a molecule composed of two monosaccharides: glucose and fructose. Sucrose is produced naturally in plants, from which table sugar is refined. It has the molecular formula C12H22011.

Answer:

table sugar is example of glucose. It has the molecular formula C12H22O11.

When flies having a gray body and normal wings were crossed with flies having a black body and vestigial wings, the F2 generation showed a phenotypic ratio of 3:1, and not 9:3:3:1.

Answers

Answer:

This proves Gregor Medel's hypothesis.

Explanation:

When Gregor Mendel crossed two pure-breed flowers, he noticed that the offspring in the F1 generation exhibited all dominant traits. However, when he crossed the offspring in the F1 generation, he noticed that the recessive trait reappeared in a 3:1 ratio (one reccesive). This is because for each trait, one allele from each parent is passed on. Also, the alleles are passed independently of one another, meaning that one allele passed for one trait won't affect the chance of another.

Other Questions
Consider an electromagnetic wave propagating through a region of empty space. How is the energy density of the wave partitioned between the electric and magnetic fields?1. The energy density of an electromagnetic wave is 25% in the magnetic field and 75% in the electric field.2. The energy density of an electromagnetic wave is equally divided between the magnetic and electric fields.3. The energy density of an electromagnetic wave is entirely in the magnetic field.4. The energy density of an electromagnetic wave is 25% in the electric field and 75% in the magnetic field.5. The energy density of an electromagnetic wave is entirely in the electric field Help pleas like please ASAP Help Please!!!Find the volume of the sphere If the constructor function is a machine to create object instances, then the _____ is the blueprint for the objects that are created. Read the prompt for a formal e-mail.Write a letter to the school board in which you propose turning part of the schoolyard into a garden.What is the purpose of the e-mail?to identify the school boards problemto solve the school boards problemto entertain the school boardto persuade the school board the longest side of a triangle is 80cm more than the second and 130cm more than the shortest side and its perimeter is 540cm. find its areahelp help Kingbird, Inc. purchased a piece of equipment for $72,200. It estimated a 8-year life and a $3,400 salvage value. At the end of year four (before the depreciation adjustment), it estimated the new total life to be 10 years and the new salvage value to be $7,200.Compute the revised depreciation assuming Kingbird uses the straight-line method.Revised annual depreciation$enter the revised annual depreciation in dollars Use the method of cylindrical shells to write out an integral formula for the volume of the solid generated by rotating the region bounded by the curve y = 2x - x^2 and the line y = x about the y-axis. Hacer una historia de hacer algo con pasin Which scenario is an example of a technological development that could cause historical accounts to change over time?Researchers find several arrowheads buried beneath a Viking church.Artifacts uncovered in the Alps show scientists that early humans dressed in fur.DNA extracted from an Egyptian mummy reveals the way the person may have died.Scientists learn about the impact of volcanic eruptions by studying remains from Pompeii. why is it important to record all data and procedures in an experiment? pha ca dao ng lm hm An eagle is flying horizontally at a speed of 2.60 m/s when the fish in her talons wiggles loose and falls into the lake 4.70 m below. Calculate the velocity (in m/s) of the fish just before it hits the water. (Assume that the eagle is flying in the x direction and that the y direction is up.) Which statement is not correct? Help me pleasee anyone If 81y^2-k=9y^2-(1/2)^2 what is the value of k With the steps pls .. Two resistors with resistance values of 4.5 and 2.3 are connected in series or parallel across a 30 V potential difference to a light bulb. a. Calculate the current delivered through the light bulb in the two cases.b. Draw the circuit connection that will achieve the brightest light bulb. 5. If a company had $15,000 in net income for the year, and its sales were $300,000 for the same year, what is its profit margin In the figure, L1 || L2. 2x=174. Find Za+Zb.