The protein calcineurin binds to the protein calmodulin with an association rate of 8.9 × 103 M-1s-1 and an overall dissociation constant, Kd, of 10 nM. The dissociation rate kd is:_____. Please explain step by step.
A. 8.9 × 10^3 M-1s-1
B. 8.9 × 10^2 s-1
C. 1.1 × 10-10 s-1
D. 8.9 × 10-5 s-1

Answers

Answer 1

Answer:

D

Explanation:

From the information given:

Association rate [tex]K_a[/tex] = [tex]8.9 \times 10^3 M^{-1}s^{-1}[/tex]

dissociation constant [tex]K_D[/tex] = 10 nM

dissociation rate [tex]K_d[/tex] = ???

Using the following relation from equilibrium dissociation constant to determine the dissociation rate, we have:

[tex]K_D =\dfrac{ K_d}{K_a}[/tex]

[tex]K_d = K_D \times K_a[/tex]

[tex]K_d =(10*10^{-9} \ M) \times (8.9*10^3 \ M^{-1}{s^{-1})[/tex]

[tex]\mathbf{K_d =8.9*10^{-5} \ {s^{-1}}}[/tex]


Related Questions

Hemophilia is an X-linked recessive condition in which blood does not clot properly. Queen Victoria of England had one allele for hemophilia. Most of her male descendants had the disorder, but few females had it. Why did hemophilia occur more frequently in Queen Victoria’s male descendants?

Answers

Answer:

Because hemophilia is an X-linked recessive condition.

Explanation:

As the problem states, hemophilia is an X-linked recessive condition.

Meaning that in Queen Victoria's female descendants (coded XX) which inherited the Queen's one allele, for hemophilia to appear in them it would be necessary to inherit another hemophillia-carrying allele from the father.The Queen's male descendants (coded XY) would always manifest hemophilia if they inherited the Queen's hemophilia allele, as they possesed only one X gene.

Summarize the steps of Scientific method in one paragraph in your own words.

Answers

Answer:

Ask a question or identify a problem.Gather information and form a hypothesis.Create an experiment to test your hypothesis.Collect data and observations by doing/ performing the experiment. Draw a conclusion.Share your findings.

If you want as paragraph:

Ask a question or identify a problem. Gather information and form a hypothesis. Create an experiment to test your hypothesis. Collect data and observations by doing/ performing the experiment. Draw a conclusion. Share your findings.

Hope it helps!

Plz mark brainliest!

Please help !
Which describes electrons?

Electrons move at very fast speeds around the nucleus of an atom.
Electrons are stationary outside of the nucleus of an atom.
Electrons move at very fast speeds inside the nucleus of an atom.
Electrons are stationary inside the nucleus of an atom.

Answers

D. Electrons move at very fast speed around the nucleus of an atom?

The ability of the human body to break down the red color in beets is controlled by an autosomal dominant allele. The inability is recessive, detected by red coloration of the urine (we will call this phenotype 'secretor'). If a nonsecretor woman with a secretor father has children with a nonsecretor man who in a previous relationship had a secretor daughter, what is the probability that their first child will be...

Answers

Solution :

It is given that a woman is a nonsecretor but the father of that woman is a secretor. It means that the father's genotype is recessive, i.e. "ss".

The genotype of the nonsecretor mother would be Ss, who have received one recessive allele from her father.

Now the nonsecretor man have a secretor daughter from his previous marriage. That means that he is a carrier nd his genotype is Ss.

Now, we can cross between the heterozygous parents (Ss x Ss) will have offspring with the following genotypes :

1 SS -- Nonsecretor

2 Ss -- Nonsecretor

1 ss -- secretor

Thus the probability that their first child will be :

a). a secretor girl

   [tex]$=\frac{1}{4} \times \frac{1}{2}$[/tex]

  [tex]$=\frac{1}{8}$[/tex]

b). Non secretor girl

     [tex]$=\frac{3}{4} \times \frac{1}{2}$[/tex]

     [tex]$=\frac{3}{8}$[/tex]

c). a secretor boy

   [tex]$=\frac{1}{4} \times \frac{1}{2}$[/tex]

   [tex]$=\frac{1}{8}$[/tex]

Por qué algunas enfermedades se padecen solo una vez?

Answers

Answer:

por que a mi saber, cuando te infectas con una enfermedad viral al contagiarte y después sanar tu cuerpo crea anticuerpos que estos asu vez hacen que seas inmune a ese virus y otras veces las enfermedades son erradicadas con la vacunación.

there are two types of white blood cell phagocyte and lymphocytes how lymphocytes work?​

Answers

Answer:

Through receptor molecules on their surfaces, lymphocytes are able to bind antigens

Explanation:

Lymphocytes are the cells responsible for the body's ability to distinguish and react

Answer:

1. lymphocytes

2. phagocytes

3. monocytes

Explanation:

100%

In the aerobic metabolism of proteins by chemoheterotrophs (e.g., E. coli and you):____.
A. Proteins are broken down into smaller peptides and eventually into amino acids by proteases (peptidases).
B. Certain amino acids may be converted to pyruvate.
C. Certain amino acids may be converted to intermediates (e.g. oxaloacetate) of the Krebs cycle.
D. Certain amino acids may be converted to acetyl-CoA.
E. All of the above are true.

Answers

The answer is A because
A) proteins are broken down into smaller peptides and eventually into amino acids by proteases

3.Each onion plant begins as a single cell containing 16 chromosomes. How many chromosomes are present in each of the cells that you observed

Answers

Answer:

In somatic cells, 16 chromosomes are present whereas in sex cells, there is 8 chromosomes.

Explanation:

In the somatic cells, the replication of chromosomes occur and after the replication is completed, the parent cell is divided into two daughter cells having double number of chromosome by each daughter cell i.e. 16 chromosomes while on the other hand, in sex cells, first the parent cell divides into two daughter cells and after sometime, these daughter cells are again divided having total four daughter cells each receives half number of chromosomes i.e. 8 chromosomes.

_______and_______process help in balancing of carbon dioxide and oxygen in the environment​

Answers

Answer: Respiration and combustion

All of the following factors contribute to the differences in complex trait risk predictions between different laboratories, EXCEPT ____________. differing methods of combining risk from multiple genetic variants selection of different genetic variants for risk determination different assessments of environmental factors genotyping of different variants

Answers

Answer:

different assessments of environmental factors

Explanation:

In humans, for predicting the future phenotype of any individual, the PSR is used.

A trait may be defined as the state of a character that is a distinct variation of the phenotypic characteristic of any organism.

The following factors contributes to the differences in the complex trait risk predictions in the different laboratories :

-- differing methods of the combining risk from the multiple genetic variants.

-- genotyping of the different variants.

-- selection of the different genetic variants for such risk determination.

Thus the factor which does not contribute is :

"different assessments of the environmental factors."

protid không phải là thành phần của

Answers

I don’t understand this question

Which molecule would be the most affected by limited nitrogen?
myofibrillar proteins in muscle

glucose molecules in starch

fat molecules surrounding organs

cellulose molecules in plant cell walls

Answers

Answer:

The molecule that would be affected by 'limited nitrogen' is the myofibrillar proteins in muscle. Explanation: The myofibrils of the muscle have a number of protein molecules.

Answer:

A

Explanation:

edge 2022 trust the process

Dark skin ( a result of increased melanin production in equatorial populations), is likely a response to ultraviolet radiation because UV radiation causes:

Answers

Answer: Skin cancer

Explanation:

Melanin is a pigment derived from an amino called acid tyrosine. The most common form of melanin is called eumelanin, which is a polymer of dihydroxyindole carboxylic acids and their reduced forms. When a person is exposed to the ultraviolet light (UV) from the sun, the melanocytes will produce eumelanin to prevent the skin from burning and damage to the cell nuclei (where DNA is found) of the epidermis. This melanin production causes the skin to darken. The eumelanin in the skin then acts as a natural sunscreen by blocking the damaging effects of sunlight. So, skin darkens when exposed UV light, thus providing greater protection when needed by producing more eumelanin, but it also becomes more likely to develop melanoma, which is a type of skin cancer. This is because UV rays damage the DNA of skin cells. The DNA (deoxyribonucleic acid) is the genetic material that has the instructios to the growth and functioning of an organisms). Skin cancers begin when eumelanin protection is not sufficient and this damage affects the DNA of the genes that control the growth of skin cells. This results in a tumor, which is the uncontrolled growth of cells (in this case, skin cells) because there will be a mutation in DNA that affects the function of the cells.

characteristics of Pisces

Answers

Answer:

Pisces are known as amazingly imaginative, creative, empathetic, and kind, they can also be overly sentimental, impressionable, and closed off.

Explanation:

Hope this helps!

an ion is formed when an atom

Answers

the basic unit of a chemical element.

Answer:

The basic unit of the chemical elements

Temperature regulatory apparatus of the mammal include the following pairs
a. epidermis and dermis
b. hair follicles and nerve ends
c. sweat glands and sebaceous glands
d. sweat glands and hair follicles​

Answers

the correct answer is D
It’s D hope this helps


What is the dewpoint temperature when the dry-bulb temperature is 12°C and the wet-bulb
temperature is 4°C?
1. -9°C
2. 19°C
3. 8°C
4. 4°C

Answers

Answer:

-9°C That is the answer

Explanation:

hope it helps!

differences between a fish and a toad.​

Answers

Answer:

⬇ See answer below ⬇

Explanation:

A fish is a(n) aquatic animal which has gills and can only find oxygen underwater. Toads are quite different though as they are amphibians who can live on both land and underwater. (Hope this helped you!)

Upon completion of seeding a flower and a vegetable, research and identify the optimum propagation conditions, such as, water and light demand, appropriate temperature, and, other elements that may affect the germination from seeding. Compare your research findings with your existing conditions. If any discrepancies found, address how you would like to mitigate. Describe the entire process in your weekly lab report journal. Add photos, sketches or other supplementary information, if necessary.

Answers

Answer:

Needs optimum environmental conditions.

Explanation:

Seedling, a flower and a vegetable needs suitable conditions for growth and development. All of the three stages of plant life cycle requires optimum water, fertilizers and light intensity in order to grow and develop at full speed. Seeds need a specific temperature in order to germinate. Most seeds germinate when the soil temperature is between 68 and 86 Fahrenheit. In the same way the plant also needs specific temperature for bearing flowers. All the stages requires optimum water in the soil for absorption.

What happens to proteins with no signal sequence that are made in the cytosol? Question 3 options: They are taken up by lysosomes. They are degraded by proteases. They are returned to their organelle of origin. They are secreted. They remain in the cytosol.

Answers

Answer:

The correct answer is: They remain in the cytosol.

Explanation:

Eukaryotic proteins are made through a process called Translation, which always starts at the cytosol (except for the proteins that are made in the mitochondria).

While Translation is taking place, the peptide that is being synthesized is checked for molecular tags that will lead to a re-routing to another destination: proteins that have an amino sequence called 'signal peptide' will be sent to the endoplasmic reticulum for its translation to continue - the proteins that go this route are meant to be part of the endomembrane system, after that they can be bounded to the ER, the Golgi apparatus or the lysosomes.

Unlike the proteins mentioned before, there are proteins that will have no signal peptide - this means that they are meant to finish Translation in the cytosol. Some of these proteins will acquire a signal tag that will lead them to the nucleus or the mitochondria, for example, but if they don't they will stay permanently in the cytosol to perform their tasks in that place.

how digestion happens in human​

Answers

Explanation:

The muscles of the small intestine mix food with digestive juices from the pancreas, liver, and intestine, and push the mixture forward for further digestion. The walls of the small intestine absorb water and the digested nutrients into your bloodstream.

Answer :Once foods are broken into small enough parts, your body can absorb and move the nutrients to where they are needed. Your large intestine absorbs water, and the waste products of digestion become stool. Nerves and hormones help control the digestive process.

what must be true about two objects if heat is flowing between them​

Answers

Answer:

The objects must be the same temperature.

Explanation:

if heat is flowing between two objects, so both ​the objects must have the same temperature because the heat in object 1 passes to the object 2 due to the conduction property present in these objects. The heat flows from one body to another body until both have the same amount of heat energy as well as temperature so that's why we can say that both objects must be the same temperature.

You are out hiking and walk past a great outcrop of granite that is part of an exposed batholith. Looking closer you notice pieces of sandstone within the batholith. Which rock is OLDER, the granite or the sandstone?

Answers

Answer:

Sandstone is younger than the granite rocks

Explanation:

As the rocks layer found at the bottom are the oldest and closer to the ground surface are the younger. This is due to the law of superimposition and as when looking at the outcrops you will notice pieces of sandstone within the batholith that indicates that the base is formed by granite and is later cemented by sandstone rock


Match the rocks with the geological processes that create them.
igneous rocks
sedimentary rocks
metamorphic rocks
They are formed when liquid
magma cools and solidifles
beneath or above Earth's
surface.
They are molded by heat and
pressure deep inside Earth.
The heat comes from magma.
Pressure is exerted by the
motion of Earth's plates and
the weight of other rocks.
They are a result of weathering
and lithification, which is often
aided by the flow of water.

Answers

Answer:

Igneous rocks:

-They are formed when liquid magma cools and solidifies beneath or above Earth’s surface.

Sedimentary rocks:

-They are a result if weathering and lithification, which is often aided by the flow of water.

Metamorphic rocks:

-They are molded by heat and pressure deep inside Earth.

-The heat comes from magma.

-Pressure is exerted by the motion of Earth’s plates and the weight of other rocks.

Explanation:

These are all I can do. You gave 5 sentence choices right? Hope this helps!

Answer:

The answer is Igneous rocks, Metamorphic rocks, and Sedimentary rocks

Explanation:

The phylogenetic tree above represents the three domains of organisms on our planet. According to this tree, organisms in domain Eukarya are closer related to organisms in domain Archaea. Organisms in kingdom Eukarya can be distinguished from organisms in kingdom Archaea by which of the following distinctions?

Group of answer choices

The presence of ribosomes for protein synthesis.

The use of a cell wall for protection and support

The presence of a nucleus in their cells

The storage of genetic material in DNA molecules.

Answers

Answer:

The storage of genetic material in DNA molecules.

the flowers of the ____ bloom with sunrise and close with sunset.​

Answers

Daylillies, or hemerocallis

IN____________ NUTRITION , THE ORGANISMS DEPEND UPON ITS HOST FOR ITS FOOD .

Answers

Answer:

heterotrophic nutrition!!

g If the sequence of bases in the DNA coding strand were CCG AGT, the sequence of amino acids in the polypeptide chain would be _

Answers

Answer:

GGCUCA

Explanation:

Define external digestion​

Answers

Answer:

Saprobionts eat by secreting enzymes through the cell membrane onto their food, a process known as extracellular phototropic digestion. The enzymes catalyze the breakdown of food into molecules small enough to be absorbed by passive diffusion, transport, osmotrophy, or phagocytosis.

-------------------------

hope it helps...

have a great day!!

Answer: External digestion is when the bacteria secretes digestive enzymes to break down the food outside of the "body" and then it sucks it up!

Explanation: her ya go

*Part 1*:
Interpretation - Identify trends, compare and contrast, draw conclusions.
The following is a plot of the number of bacterial cells vs time in a culture. A culture refers to
cells grown in a man-made environment. For example, even though oceans, streams and
ponds are teaming with microbes, they are not considered a culture because they are part of a
natural environment. Yogurt as well as cells grown on agar plates or liquid cultures are
examples of a man-made environment.
c.
b.
d.
a.
5
Time (hr)
10
*Part 1*: Analyze the image. Be sure to include a conclusion. There are no incorrect
conclusions, only illogical ones.
Answer:

Answers

Answer:

First increases, attain highest population and then decreases.

Explanation:

In the culture, the number of bacterial cells increases with the passage of time in a culture. at the beginning, the bacterial cells increases in number or population with the passage of time. At point C, it shows highest population of bacterial cells at the time period of 4 to 5 hours but after more time passed, the population of bacterial cells decreases may be the unavailability of food substances in the medium.

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