Individuals with a mutation in the gene for apolipoprotein B-100 produce very low levels of this protein, which is a component of LDL. How would accumulation of fat in the liver be affected and would this result in hypercholesterolemia or hypercholesterolemia

Answers

Answer 1

Answer:

Fats would accumulate in the liver and the individual would show hypocholesterolemia

Explanation:

Familial hypercholesterolemia is a genetic disorder caused by a reduction and/or defect in the low-density lipoprotein (LDL) receptor. Moreover, apolipoprotein B is the unique protein component of LDL, which plays a critical role in lipid metabolism by binding the LDL receptor. Familial defective apolipoprotein B-100 refers to an inherited disorder associated with mutations of the apolipoprotein B-100 that leads to moderate or severe cases of hypercholesterolemia. Mutations in apolipoprotein B-100 are associated with a reduction in the binding capacity of LDL to the LDL receptor, thereby leading to hypercholesterolemia.


Related Questions

As more is learned about cancer, it has become clear that cancer, with few exceptions, ________. Group of answer choices is only dependent on the inherited genetics is a result of genetics and environmental factors is 100% dependent on inherited genetics has no genetic basis

Answers

Answer: Is a result of genetics and environmental factors.

Explanation:

Cancer is the common name for a group of diseases in which there is a division of the body's cells, whose growth exceeds that of normal tissues and which persists in the same excessive manner. It can begin in a localized manner and spread to other surrounding tissues and its malignancy is very variable, according to the aggressiveness of its cells and other biological characteristics of each type of tumor. In general, the behavior of cancer cells is characterized by lacking the reproductive control required by their original function, acquiring the capacity to invade tissues (metastasis), spreading through the organism via the lymphatic or circulatory system, and causing the growth of new tumors in other parts of the body.

A gene is a hereditary unit composed of DNA that carries the instructions for producing proteins, which do much of the work in our cells. Certain genetic alterations can cause cells to evade growth controls and become cancerous cells. These changes can be inherited from our parents if the changes are present in the germ cells (eggs and sperm) and they are called germline changes. In addition, cancer-causing genetic changes can also be acquired during a person's lifetime (somatic or acquired changes), as a result of DNA errors that occur when cells divide either spontaneously or by exposure to carcinogenic substances that damage DNA (environmental factors), such as certain chemicals in tobacco smoke, or radiation, such as ultraviolet rays from the sun. These substances damage DNA, acting as mutagens.

Sometimes, the changes are not in the DNA sequence. For example, the epigenetic modifications are the presence of chemical marks in DNA which can determine if the gene is expressed. This means, whether and how much messenger RNA is produced, because the messenger RNA is translated into proteins.

So, cancer cells have genetic changes compared to normal cells. These changes are due to mutations that can be inherited, acquired spontaneously during life, or acquired due to environmental factors such as sun exposure, smoking, and other factors. In addition, the fact that a person has the cancer-related mutation does not necessarily mean that he or she will develop the disease during his or her lifetime. In some cases, even if they have this genetic vulnerability, they remain healthy, because cancer is a multifactorial disease that depends on many factors, such as the immune system, nutrition and certainly many others currently unknown to medicine.

What is species definition

Answers

Answer:

a race of animal

Example:

a wolf and a dog are the same species

Answer:

a group of living organisms consisting of similar individuals capable of exchanging genes or interbreeding. The species is the principal natural taxonomic unit, ranking below a genus and denoted by a Latin binomial

A type of animal.

What is a gene??????

Answers

Answer:

A gene is a unit of heredity

Explanation:

A gene is a unit of heredity that is passed from a parent to their offspring and is responsible for determining a certain trait of the offspring.

or

A gene is a unique sequence of nucleotides that makes up a chromosome and controls how a cell (or virus) can assemble monomers into polypeptides or nucleic acid molecules.

Which of these statements about photosynthesis is correct?
A.
Both photosynthesis and respiration require the same amount of energy for metabolic processes, such as synthesis and the breakdown of carbohydrates.
B.
Photosynthesis releases energy for metabolism, whereas respiration requires energy for the breakdown of carbohydrates.
C.
Photosynthesis requires energy for the synthesis of carbohydrates, whereas respiration releases energy during the breakdown of carbohydrate

Answers

Answer:

C

Explanation:

112g Fe + 64g S = FeS

Answers

The correct answer is 176 g

Skin cells are lost daily even without injury. The cell cycle responds by promoting
a. reproduction.
b. repair.
c. synthesis.
d. growth.

Answers

Answer:

The correct answer is A

Hope it helps! Please mark me Brainliest!

The cell cycle responds to the daily loss of skin cells skin promoting reproduction. Details about reproduction can be found below.

What is reproduction?

Reproduction in biology refers to the process of making copies or duplicate of a cell.

According to this question, skin cells are lost on a daily basis even without injury.

However, the cell cycle through the process of mitosis responds to this loss by making more copies of skin cell in a process of reproduction.

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Genetic engineering involves various stages.

1 human DNA is inserted into bacterial plasmid DNA
2 recombinant plasmid inserted into bacteria
3 restriction enzyme cuts bacterial plasmid DNA
4 restriction enzyme cuts human DNA

What is the correct sequence for genetic engineering?​

Answers

Answer:

4, 3, 1, 2

Explanation:

FIRST: cDNA is synthesized to be used as a gene of interest: processed (spliced) mRNA (no introns) is reverse transcribed to cDNA using reverse transcriptase, an enzyme from retroviruses

SECOND: Restriction enzyme used to cut GOI

THIRD: Same Restriction enzyme used to cut plasmid (sticky ends are created)

FOURTH: GOI connects/hybridizes with plasmid due to base-pairing

FIFTH: DNA ligase connects the recombinant DNA strands

From earliest to latest, the overall sequence of early development proceeds as follows: A) gastrulation → organogenesis → cleavage B) ovulation → gastrulation → fertilization C) cleavage → gastrulation → organogenesis D) gastrulation → blastulation → neurulation E) preformation → morphogenesis → neurulation

Answers

Answer:

C) cleavage → gastrulation → organogenesis

your welcome!

How far is the moon from the sun?

Answers

Answer:

150 million kilometers

Explanation:

The Moon is approximately 150 million kilometers from the Sun on average. Because the Earth orbits the Sun at a distance of roughly 150 million kilometers, this is a fascinating coincidence. Because the Moon orbits the Earth, it follows the Earth's orbit around the Sun.

OAmalOHopeO

What is a similarity between the temperate climate zone and polar climate zone?

A. Both climate zones get less than 100 cm of precipitation in a year.
B. Both climate zones have average yearly temperature of around 25°C.
C. The polar and temperate climate zones have hot and dry summers.
D. They have hot summers and cold winters because they are close to the ocean.

Answers

Answer:

may be option c or b I think but I am not sure

¿En qué momento se produce la hinchazón del tejido?

Answers

Answer:

Es el agrandamiento de órganos, piel u otras partes del cuerpo, causado por la acumulación de líquidos en los tejidos. La presencia de líquido extra puede llevar a un aumento rápido de peso durante un período corto (de días a semanas).

A bacterial cell wall is composed of: A) A polysaccharide consisting of a single type of monosaccharide unit and cross-linking oligopeptides. B) A polysaccharide consisting of 2 types of monosaccharide units and cross-linking oligopeptides. C) A polysaccharide consisting of 3 types of monosaccharide units and cross-linking oligopeptides. D) Two different polysaccharides and 1 type of oligopeptide, which are cross-linked.

Answers

Answer:

B) A polysaccharide consisting of 2 types of monosaccharide units and cross-linking oligopeptides.

Explanation:

A cell can be defined as the fundamental or basic functional, structural and smallest unit of life for all living organisms. Some living organisms are unicellular while others are multicellular in nature.

Also, a unicellular organism refers to a living organism that possess a single-cell while a multicellular organism has many (multiple) cells.

A bacterial cell is made up of peptidoglycan and its main function is to maintain the shape of a cell while preventing it from bursting due to osmotic pressure. Also, the bacterial cell inhibits the passage of larger molecules but allows the free movement (passage) of smaller molecules in the body of a living organism.

Basically, bacterial cell wall comprises a polysaccharide that's typically made up of two (2) types of monosaccharide units and cross-linking oligopeptides.

In your own words, what is the definition for the word karyotype?

Answers

Answer:

Karyotype is defined as the general appearance of chromosomes. An example of karyotype is the size, number and shape of chromosomes in a person's body. noun. The characterization of the chromosomal complement of an individual or a species, including number, form, and size of the chromosomes. noun.

the personality of an individual involves his or her​

Answers

Answer:

both

Explanation:

depends on the person's personality I guess or how they act n all

A man is brachydactylous (very short fingers; rare autosomal dominant), and his wife is not. Both can taste the chemical phenylthiocarbamide (autosomal dominant; common allele), but their mothers could not. Give the genotypes of the couple. If the genes assort independently and the couple has four children, what is the probability of all of them being brachydactylous

Answers

Answer:

The correct answer is -

A) BbTt x bbTt

B) .5^4 or 1/16 or 0.0625

Explanation:

As it is given that Brachydactylus and PTC tasters both traits are autosomal dominant conditions which mean only one allele would be enough.

For Branchydactylus and For tasting :  man and women will be heterogeneous.

Hence,

The Genotype of man = BbTt

The Genotype of wife = bbTt

b. Answer = 0.0625

For Branchydactylus:

Bb X bb

Possible genotypes:

B b

b Bb( Brachydactylus) bb(normal)

b Bb (Brachydactylus) bb (normal)

The probability of a single child being Branchydactylus = 2/4 = 0.5

So,  Probability of all 4 child being Branchydactylus = .5 x .5 x .5 x .5 = 0.0625

1. Explain using diagram how monomers are arranged in Thermoplastic and Thermosettingplastics.​

Answers

Explanation:

In thermoplastics, the arrangement of monomeric units is linear and in thermosetting plastics, it is cross-linked. Thermoplastics are usually soft, weak and less brittle, so can get soften on heating and stiffen on cooling. They can be melted, remoulded and recycled easily.

3 adaptive features of amoeba​

Answers

Answer:

3

Explanation:

because yes

Answer:

They reproduce using binary fission

It contract their vacuoles

Amoeba breathe through the body surface

What is the role of the fungus in the food web shown?
boa constrictor
beetle
- coati
poison dart frog
sloth
strangler fig
fungus fruit bat
A. To recycle molecular building blocks
a
B. To break down photons
C. To gather green light
O D. To convert light energy into chemical energy

Answers

Answer:

OptionA    because decomposers are associated

Explanation:

The role of the fungus in the food web shown is to recycle molecular building blocks. The correct option is A.

What is food web?

A food web is a diagram that depicts the interconnection of various organisms in an ecosystem via the exchange of energy and nutrients.

The food web is made up of several interconnected food chains that represent the flow of energy from one organism to the next.

Fungi are decomposers that play an important role in breaking down organic matter and recycling nutrients in many ecosystems.

The fungus in the food web is most likely breaking down dead plant or animal matter, releasing nutrients like carbon, nitrogen, and phosphorus back into the soil.

These nutrients are then absorbed by plants, which are then consumed by herbivores such as the coati and sloth.

Thus, the correct option is A.

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According to the ESRT, the rate of temperature increases below the Earth's surface is greatest between depths of

Answers

Answer:

Between depths of tectonic plate boundaries and the outer core.

Explanation:

The rate of temperature increases below the Earth's surface is greatest between depths of tectonic plate boundaries and the outer core.  At the depth, some of the heat comes from the Earth's core while most of the heat comes from decay of radioactive elements, mainly uranium, thorium and potassium that is located in rocks of the crust. So we can say that the the increase in temperature with depth varies with the chemical composition and age of the rocks.

Please help me to fill in the blanks. Thanks!

Sediments minerals rock remains sedimentary millions

When animals and plants die, their bodies fall into __________. Some of these decays while some become part of ______________ rocks. Rock layers build up and the rock becomes a solid. The ______________ in the rock replace the ________________ in parts of dead bodies. This takes place over _______________ of years. The_______________ of living organisms that have changed to ________________ are fossils.

Answers

When animals and plants die, their bodies fall into sediments. Some of these decays while some become part of fossilized rocks. Rock layers build up and the rock becomes a solid. The minerals in the rock replace the soft parts in parts of dead bodies. This takes place over millions of years. The remains of living organisms that have changed to stone are fossils.

what is homostatis in biology​

Answers

Answer:

the tendency toward a relatively stable equilibrium between interdependent elements, especially as maintained by physiological processes.

It means “same”, and “steady”, and it refers to any process of organisms that live under actively maintain fairly stable conditions necessary for survival.

In humans, one function of an inter neuron is to relay impulse directly from …

Answers

Answer:

D

Explanation:

the interneuron is located in the central nervous system between the sensory neuron and the motor neuron, therefore it relays impulses from the sensory neuron to the motor neuron

I hope this helps

Paula has studied the effect of ultraviolet light on seed germination.
Data were collected on seeds that were exposed to UV radiation and
then allowed to germinate. Which statement is true concerning this
data? *
O UV rays help seeds germinate.
O Temperature is insignificant.
There is no control group.
UV light is toxic to seeds.

Answers

Answer:

i dont know

Explanation:

One gene pair can influence other gene pairs, with their combined activities producing some effect on phenotype; this called ________________. In Labrador retrievers, one gene pair codes for the quantity of melanin produced while another codes for melanin deposition. Still another gene locus determines whether melanin will be produced at all--lack of any produces an albino (recessive).

Answers

Answer:

Epistasis

Explanation:

Genetics can be defined as the scientific study of hereditary in living organisms such as humans, animals and plants

In Genetics, a gene pair has the ability to influence other gene pairs based on their combined activities which produces some effect on phenotype; this is called epistasis.

Which is an effect of an increase in ocean temperature?
A. Increased precipitation
B. Increased percolation
C. Decreased evaporation
D. Decreased transpiration

Answers

Answer:

a

Explanation: because the increased tempuature will result in an increase in evaporation which in  turn increases precipatation

A cell is round and cannot produce its own food. Which organelle does this cell have?(1 point)

A:central vacuole

B:cell wall

C:plasma membrane

D:chloroplast

Answers

Answer:

may be c is thw correct answer

You are overseeing a paleontological expedition at the Grand Canyon to uncover fossils. You have one group working about 10 feet above the bottom of the canyon,
uncovering a cluster of Brachiopods You have a second group working about 300 feet above the bottom of the canyon, uncovering impressions from a variety of plants
such as fems and horsetails. While you are waiting for the exact age of the rock layers to be determined, what can you tell about the age of the fossils based on
where they are
A. You cannot determine anything yet.
B. They are all about the same age.
C. The plants must be older than the Brachiopods.
D. The Brachiopods must be older than the plante

Answers

Answer:

C

Explanation:

because the plants are farther down lol

Paleontology establishes the geological age of the organisms. Based on the height of the fossils discovered at the Grand Canyon, it can be concluded that plants were older than the Brachiopods. Thus, option C is correct.

What are fossils?

The dead remains and decaying materials of the plants and animals stored and preserved under the sediments and rock layers over a period of many years are said to be called fossils.

The fossils are evidence of the evolution as well are used to determine the geological age of the species based on their occurrence of them in the rock layers.

The fossils of plants like horsetails and ferns were found 300 ft above the Canyon while Brachiopods at 10 feet above Canyons that tell that plants were found earlier than the former species.

Therefore, option C. the plants existed prior to the Brachiopods.

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how is the frictional force produced?​

Answers

Answer:

Frictional force refers to the force generated by two surfaces that contacts and slide against each other, If an object is pushed against the surface, then the frictional force will be increased and becomes more than the weight of the object

When the flow of water cuts very deep channels through the earth *
2 points

Answers

Answer:

It  carves deep into the rock and soil it flows over. Mountains streams cut narrow V-shaped channels

Explanation:


Write the changes occurring in the passage through the alimentary canal as a person has ingested roti and dal as a part of his meal

Answers

Answer:

A person had roti and dal for his lunch. Trace the changes in those during its passage through the alimentary canal. Answer: ... The saliva contains an enzyme salivary amylase (ptyalin) which converts starch in roti into maltose, isomaltose and small dextrins called a-dextrin.

Explanation:

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