Galactosemia is a metabolic disorder characterized by the inability to metabolize the sugar galactose. People with galactosemia suffer from liver, kidney, and brain damage among other symptoms. A gene mutation underlying galactosemia was identified by sequencing the genome of a person with galactosemia. What additional evidence would support the hypothesis that the mutation in the candidate gene causes the disease

Answers

Answer 1

Answer:

Genetic mapping for unequivocal identification of the potentially causative mutation  

Explanation:

Galactosemia is a genetic disorder caused by mutations in the Galactose-1-phosphate uridylyltransferase (GALT) gene, which encodes an enzyme involved in the metabolism of galactose. Gene mapping is a technique widely used in genetics to identify the position of one locus a chromosome by using molecular markers to estimate genetic distances. Genetic mapping provides useful evidence in order to identify when a disease that is transmitted from parent to offspring can be associated with one or more genes and then determine which gene/s is/are responsible for this condition.


Related Questions

Each of two parents has the genotype brown/red​, which consists of the pair of alleles that determine hair color​, and each parent contributes one of those alleles to a child. Assume that if the child has at least one brown ​allele, that color will dominate and the​ child's hair color will be brown. a. List the different possible outcomes. Assume that these outcomes are equally likely. b. What is the probability that a child of these parents will have the red/red ​genotype? c. What is the probability that the child will have brown hair color​? a. List the possible outcomes.

Answers

Answer:

a. In image attached.

b. 25% or a 1 in 4 chance.

c. 75% or a 3 in 4 chance.

Explanation:

B = Dominant (brown gene)

r = Recessive (red gene)

If two parents both have Br genes, they will both have brown hair.

The Punnet square will look like the image attached.

explain the scientific theory of evolution and the evidence scientist found that proves it to be valid ?

Answers

Answer:

There are many theories

But main evidences are

Fossils of Plants animals and other organisms who lived on this planet at sometime. Oprain And Halden theory which suggests the chemical and biological evolution.

After entering a dark room, you turn on a light switch, but the light does not come on. Please suggest three different hypothesis that might explain your observation. Please also note how you might test these hypotheses and describe what observation(s) may lead you to conclude that one of the hypothesis is correct.

Answers

Answer:

First hypothesis; may be the power is cut. ( no power supply) Second hypothesis; may be the light switch is defective ( wall switch not working )Third hypothesis; maybe the bulb is burnout  ( light bulb may not be working )

Explanation:

The three possible hypothesis for light not to turn on immediately after one on the switch are;

First hypothesis; may be the power is cut. ( no power supply) Second hypothesis; may be the light switch is defective ( wall switch not working )Third hypothesis; maybe the bulb is burnout  ( light bulb may not be working )

We test the first hypothesis, how?

We check if other electronics connected to the same sources of power supply as the bulb is working. If the electronics are not working, then the first hypothesis is correct but if they are working then the hypothesis fails and we move on to test the next hypothesis.

To test for the second hypothesis as the first hypothesis fails, we remove the bulb and fix it into another socket which has a working switch. If the bulb comes on then the second hypothesis is correct but if the bulb does not turn on then the hypothesis fails so we move on to test the third hypothesis.

As the bulb fails to turn on in our initial socket and a second bulb is fixed in that same socket and it came on, then the third hypothesis is correct.

The three hypotheses we can derive from entering a dark room, turning on a

light switch,and the light not coming on include

There may be no power source at that momentThe bulb may be faultyThe switch may be faulty

A power source helps to provide energy to power up an appliance and where it is absent, the bulb won't light up.

A defect in the switch and bulb may also hinder the light from coming on as

the switch controls electric current flow while the bulb produces the light.

Read more about Hypothesis here https://brainly.com/question/12416923

PLEASE ANSWER QUICK!The Greek roots of the word prokaryote mean “before nucleus.” Describe the way that DNA is organized in prokaryotic cells without the help of a nucleus. How does this approach differ from the way that eukaryotic cells organizes their DNA

Answers

Answer:

Prokaryotic cells' DNA are located in the cytoplasm of the cell rather than in the nucleus, like in eukaryotic cells. DNA aids in protein synthesis and determines functions of the cell in cells, regardless of being within the membrane of a nucleus or not.

-----

I hope this helps a little.

The word prokaryote in Greek means before kernel (nucleus). Unlike the eukaryotic cells, the nuclear material is located in the cytoplasm of the cell in a nucleoid.

What are the characteristics of prokaryotic cells?

The prokaryotic cells are the primitive karyons that are defined by the lack of the true nucleus and organelles. Unlike the eukaryotes, the organelles lack the membrane that covers them but has a tough cell wall.

The prokaryotes include archaea and bacteria which are unicellular and microscopic organisms that are simple and have their genetic material organized into nucleoids in the center of the cell. They have the ability to live in harsh conditions.

Therefore, the eukaryotes and prokaryotes differ in the arrangement of the genetic material.

Learn more about prokaryotes, here:

https://brainly.com/question/18348786

#SPJ2

Butterflies can produce hundreds of offspring per cross. In a certain variety of butterflies, a maternally-imprintable gene is responsible for wing phenotype. Two possible alleles for this gene are w for normal wings and wc for crinkled wings. Which of the following pieces of information would be helpful in predicting the wing phenotype of a male offspring from a cross?

a. look at the father's phenotype
b. know the mother's genotype
c. look at the mother's phenotype
d. know the father's genotype

Answers

Answer: d. know the father's genotype

Explanation: Butterflies can produce hundreds of offspring per cross. In a certain variety of butterflies, a maternally-imprintable gene is responsible for wing phenotype.

The option that would be helpful in predicting the wing phenotype of a male offspring from such a cross would be to look at the father's phenotype.

Imprinted genes can simply be defined as genes that are expressed in parent-of-origin specific manner and result from a chemical modification of DNAs.  Such genes are differentially expressed depending on which of the two parents they are inherited from. Hence:

maternally-imprintable genes are only expressed when they are inherited from the father. paternally-imprintable genes are only expressed when inherited from the mother.

Phenotype refers to the physical appearance or expression of a gene. Therefore, if a gene is maternally imprintable, looking at the phenotype of the father would be helpful in predicting the phenotype of the male child in case a cross happens.

Applying the same principle to the butterfly, it will, therefore, be helpful to look at the father's phenotype in order to predict the wing phenotype of a male offspring from a cross.

The correct option is A.

More about imprinted genes can be found here: https://brainly.com/question/7207412

On April 26, 1986, Reactor 4 at the Chernobyl Nuclear Power Station in Ukraine exploded, releasing radioactive isotopes into the air. The majority of the isotopes that were released and spreading thousands of miles were of the element iodine. As a class, discuss what endocrine glands would be most affected and how it would become apparent in the nearby population.

Answers

Answer:

In the given case, the thyroid gland will be affected the most due to the exposure of the element iodine. For the synthesis of thyroid gland hormone, T3 and T4 iodine is required. As the exposure of the radioactive iodine element is taking place, therefore, it will result in the deterioration of the thyroid gland. Radioactive iodine is generally used in the treatment of hyperthyroidism.  

However, in normal individuals, the exposure of the radioactive iodine element results in a decrease in the level of thyroid hormones below the normal level due to the destruction of the thyroid cells. The symptoms seen can be neck tenderness, swollen salivary gland, and loss in body weight.  

The thyroid gland will be mostly affected in this case. The element Iodine is

the major precursor which is involved in the formation of two hormones.

Thyroid hormonesTriiodothyronine (T3)Thyroxine (T4).

When an individual is exposed to radioactive iodine , it alters the production

of the hormones which leads to series of effects such as:

Decreased metabolismLow body weightGoitre etc.

Read more about Thyroid hormones here https://brainly.com/question/2469666

Please answer ASAP, the assignments in due really soon :) 30 Points!!! The image below shows the lac operon, which breaks down lactose in bacteria. Which statement correctly describes the expression of this gene?

Answers

Answer:

B. Gene expression is influenced by high lactose levels in the environment.

Explanation:

The lactose operon (lac operon) functions for the metabolism and transport of lactose in several bacteria.

Gene expression is influenced by high lactose levels in the environment as genes are expressed in the presence of high level lactose and absence of glucose. High level lactose carry an activator protein called catabolite activator protein (CAP), which let the RNA polymerase do transcription of the operon.

Hence, the correct option is "B".

Answer:

C

Explanation:

^he said it was right^

have an amazing day! :)

A 23 year old female presents with bilateral loss of central vision. You obtain a detailed family history and produced the associated pedigree. Which of the following transmission patterns is most consistent with this patient's family history?

a. Autosomal dominant
b. Autosomal recessive
c. X-linked dominant
d. X-linked recessive
e. Mitochondrial

Answers

Answer:

e. Mitochondrial

Explanation:

This is a case of mitochondrial heredity so correct answer is e. Mitochondrial In this case, the mother transfers her mitochondria to her children. So the child is affected. The male does not pass this trait on to his children. We can see from the lineage that the mother has defective mitochondria so all their children will have defective mitochondria. One of his sons has mitochondrial, but is unable to pass it on to the next generation.

Which statement best describes a hypothesis?

Answers

Answer:

A hypothesis is an idea or explanation you can test through study and experimentation.

Explanation:

What energy transformations are going on within the skateboarder’s body during this process?

Answers

Answer:

When they slide down, they lose this potential energy, which turns into kinetic energy and thermal energy. Thermal Energy - This energy is related to the temperature of a body or a system. When friction is involved in a system, part of the kinetic energy is transformed into thermal energy.

The idea that chromosomes orient themeselves randomly during metaphase I is ________________________. This leads to ___________________ combinations of genes.

Answers

Answer:

The idea that chromosomes orient themselves randomly during metaphase I is Independent Assortment. This leads to more combinations of genes.

Explanation:

During metaphase I, the pair of chromosomes align in the plate of the cell. In this step, the independent assortment takes place.

The independent assortment is the distribution of different genes into two gametes, is independent, because the distribution of the different genes, does not influence the distribution of the other genes. The independent assortment leads to new combinations of genes from the parental and maternal side, resulting in offsprings that do not look exactly like their parents.

Place the following materials in the order in which they are likely to fossilize. Begin with the material that is most likely to fossilize, and finish with the material least likely to fossilize.
1. mammal teeth
2. bones of an adult mammal quickly buried
3. bones of an adult mammal left on the surface
4. soft body parts of any animal

Answers

Answer: correct order--->

1)mammal teeth

2.)bones of an adult mammal quickly buried

3.) bones of an adult mammal left on the surface

4.)soft body parts of any animals

Explanation:

Fossilization is the ability of an organism to be preserved and remain unaltered for a very long time. Through research , it has been found out that Harder  parts of the body tend to remain preserved for a long time  because they  naturally have minerals deposited in them and may only be reduced,  but the softer part or tissues do not get preserved for a long time because being made up of polymer can be disintegrated easily by natural biological and physical processes.

The order of which material will likely fossilize is

1.)mammal teeth

2.)bones of an adult mammal quickly buried

3.) bones of an adult mammal left on the surface

4.)soft body parts of any animals

Reason,

--Teeth and bones biologically contain calcium but the teeth is more tougher and durable than the bone, Even when a  body is decomposed, the teeth most times are not  affected at all.

Bones of an adult mammal left on the surface will decompose faster than the one buried because of the biological (natural decomposing ) and physical processes(temperature, wind, sunglight, rainfall ) which will both act on it at the same time because of its exposure.

- soft body parts of any animals will decompose fastest as bacteria will feed on it immediately since it lacks minerals that can elongate preservation.

Describe how protein functional groups can act as acid and base catalysts. How is it possible for a single amino acid side chain to function as both?

Answers

Answer:

By changing the transition state and pH of the medium

Explanation:

Enzymes are proteins that bind to their corresponding substrates at their active sites in order to form complexes that catalyze specific chemical reactions. A key feature of this process is the fact that both acid and base catalytic activities may be combined in the same reaction. The acceleration in the velocity of the enzymatic reaction due to the addition of acids and bases is known as acid–base catalysis, where the acid or base is not consumed during the reaction. For example, enzymes can partially transfer a proton to the medium, thus changing the transition state of the chemical reaction and also decreasing its pH.

5. According to the video, what is the goal of the tree of life?
a. To summarize a fossil record
b. To describe how natural selection works
To be a library of all life that has ever lived
d. To explain how all species are related to each other

Answers

To be a library of all life that has ever lived

Which are the 3 major areas of society affected by science?

Answers

Answer:

Explanation:

the three major areas of society affected by science are economic democratic and cultural

mark me brainlist if my answer is right

Describe the intermolecular interaction of the surface carboxylate groups of a micelle and the surrounding water.

Answers

Answer:

Hydrophilic portions are outside and hydrophobic regions are inside

Explanation:

A micelle is an assembly of amphiphilic molecules formed in a liquid solution, generally an aqueous solution. Micelles are formed due to the packing (aggregation-like) behavior in which single-tail lipids are organized in a bilayer. A typical micelle in aqueous solution forms a spheric assembly where carboxylate ions are organized in a mode that hydrophilic head regions enter in contact with the surrounding water, while hydrophobic (lipophilic) portions are disposed inside the micelle.

Challenge Question! If a pregnant woman had a karyotype prepared for her baby before birth, would it be more useful in predicting the risk of Down Syndrome or Tay Sachs disease?

Answers

Answer:

Yes

Explanation:

Karyotype involves the process of viewing a persons chromosomes through Sophisticated equipments.

Down Syndrome or Tay Sachs disease are genetic diseases associated with chromosomal defects.

Having a karyotype prepared for her baby before birth, would be more useful in predicting the risk of Down Syndrome or Tay Sachs disease.

Genes, Chromosomes, and DNA Quick Check
If one half of a DNA molecule has 8 thymine bases, what else is also true about the DNA molecule? ( point)
There will be 16 total bases.
There will be 32 total bases.
There will be 8 adenine bases.
There will be 8 cytosine bases.

Answers

Answer:

There will be 8 adenine bases.

Explanation:

There are total of 4 nitrogenous bases present in a DNA that includes Adenine, Guanine, Thymine, and Cytosine. These nitrogenous bases form complementary base pair in which, adenine form two hydrogen bonds with thymine and cytosine form three hydrogen bond with guanine.

So, if there are 8 thymine bases in a DNA (irrespective of half or full) then there will be 8 adenine bases, forming two hydrogen bond with each other.

Hence, the correct answer is "There will be 8 adenine bases."

What is a CAFO? Spell out what the acronym stands for. Briefly describe what the animals experience there. How does the way they are treated also affect us?

Answers

Answer:

Concentrated Animal Feeding Operation

Explanation:

CAFO stands for Concentrated Animal Feeding Operation.

CAFO helps in the efficient care of the animals. They are provided with good food sources and also help provide a standard shelter for their optimal production.

It affects us as there is a high probability on the presence of cheap and high quality livestock products such as egg, meat etc due to the efficiency in animal care carried out.

HELP!!! Plato Biology closed out and all I had left was Final. Anyone have examples of the 50 questions so I can study

Answers

Answer:

Explanation:

Are gender traits completely a result of societal expectations?

Are there any parts of the human body that get oxygen directly from the air and not from the blood?

Are there nuclear reactions going on in our bodies?

Can humans ever directly see a photon?

Can I turn my cat into a diamond?

Do blind people dream in visual images?

Do Kirlian photographs show the soul of an organism?

Do koalas eat honey like other bears?

Do poppy seeds contain narcotics?

Does the human body contain minerals?

How can the heart be strong enough to pump blood up your legs against gravity?

How can we differentiate so many different foods if we can only taste four flavors on our tongue: sweet, bitter, sour, and salty?

How can we unlock the 90% of our brain that we never use?

How did doctors create my belly button?

How did evolution ever lead ostriches to hide their head in the sand when an enemy approaches?

How do I turn on more parts of my brain and get smarter?

How do nerves control every organ and function in the body?

How do trees give earth all its oxygen?

How does the outer layer of skin cells on my finger detect when I am touching an object?

How long before genetic sequencing is able to tell us exactly how our children will look and act?

How long does it take our eyes to fully adapt to darkness?

How much water can a camel store in its hump?

How strong does a non-toxic odor have to be before it damages your sense of smell?

Is human blood ever any color other than red?

Is ionizing radiation always harmful?

Is it completely random whether a baby is a boy or a girl?

What are the five senses of the human body?

What chemicals can make human tissue regenerate in seconds?

What is it about a full moon that makes people do crazy things and commit crimes?

What is it about red that makes bulls so angry?

When did humans stop evolving?

When do birds use their teeth?

Where in my body is the original cell from which I was formed?

Why are bats blind?

Why are human brains the biggest?

Why are red, yellow, and blue the primary colors in painting but computer screens use red, green, and blue?

Why are veins blue?

Why can only certain parts of the tongue taste sweet flavors? Is there an evolutionary benefit to this?

Why can you boil a frog without it jumping out to safety if you raise the temperature slowly?

Why can't color blind people see any colors?

Why did evolution create a chicken that lays so many unfertilized eggs when that is so wasteful?

Why do camera flashes make your eyes turn red?

Why do humans have an appendix even though it is unnecessary?

Why do my fingers absorb water and become wrinkled?

Why does chewing gum take seven years to digest?

Why does every cell in our body contain DNA?

Why does evolution always lead to more advanced species?

Why don't dogs sweat?

Why don't I burst cells in my rear when I sit down?

Why don't our eyeballs fill up with water when we swim?

Why don't trees freeze and burst in the winter like cold pipes?

Why have humans evolved to be taller over the last three hundred years?

Why will a mother bird abandon its chick if touched by a human?

define factors affecting enzyme action:temperature

Answers

Answer:

I am secondary level student and this doesn't belongs to my coure till yet however..i have written this through google.....you may search there as well..

Explanation:

Enzyme activity occurs within a narrow range of temperatures compared to ordinary chemical reactions. As you have seen, each enzyme has a certain temperature at which it is more active. This point is called the optimal temperature, which ranges between 37 to 40C°...

Temperature. As temperature increases to the optimum , the kinetic energy of the enzyme and substrate increases, causing more collisions between the enzyme and substrate.

The ion composition of perilymph is like that of interstitial fluid; high sodium and low potassium levels. If someone ruptured the vestibular membrane, the membrane between the vestibular duct (Scala vestibuli) and the cochlear duct (Scala media), what would be the effect of such a rupture on the concentration of potassium in the endolymph in the cochlear duct

Answers

Answer:

The concentration of potassium will decrease

Explanation:

The cochlear ducts are composed of two distict types of fluids: 1-perilymph, rich in sodium (140 mM) and low in potassium (5 mM), and 2- endolymph, rich in potassium (1 mM) and low in sodium (150 mM). The perilymph fluid has a similar composition to the rest of the extracellular fluids, while endolymph present a unique ion composition that is not found in other fluids of the body. It is believed that the cochlea can regulate potassium flow without using energy (i.e.,  without use ATP), since potassium enters into the cells through passive pathways, while this ion ion leaves the cells by an active mechanism.

When a liquid becomes a gas, _____

The molecules move closer together
The molecules move farther apart
The molecules are unchanged
There are no molecules

Answers

Answer:

The molecules move farther apart.

In prokaryotic cells, regulator proteins bind to a section of DNA called alan (1 point)
O repressor
o promoter
O chromatin.
o operon.

Answers

Answer:

promoter

Explanation:

Answer: Operon

Explanation:

PLS HELP ME OUT WITH THIS ANSWER........ WHAT IS DINOFLAGELLATES ?

Answers

Answer:

These are single-celled MESOKARYOTES constituting the phylum DINOFLAGELLATA

Explanation:

Their populations are distributed depending on sea surface temperature,e.t.c.

Hope it helps.

• They are basically unicellular, motile, biflagellate and photosynthetic protists. Predominate colour is golden brown but yellow, green, red and even blue also exists.Some Dinoflagellates like Gymnodinium and Gonyaulax grow in large number in the sea and make the water look red and cause the so called “red tide”.

What type of muscle is found in the circulatory system?

Answers

Answer:

The heart is the pump and the vessels are the delivery and return system for the blood. Every tissue in the body, directly or indirectly, receives oxygen and nutrients from blood supplied by the cardiovascular system. The heart is a muscle. The muscle is a modified form of skeletal muscle called cardiac muscle.

Explanation:

i hope itt help you

Answer:

blood muscles are found

Most adults should consume no more than 30 percent of their daily calories from fat. A person on a daily diet of 2,500 calories should get no more than how many calories from fat each day.

Answers

Answer:

750

Explanation:

30% of 2,500 is 750, therefore 750 calories is the maximum number one should get from fat each day.

Answer:

750  marry christmas break

The photoelectric effect describes when light shines on a piece of metal, and the metal releases electrons. Which model of light
behavior best helps explain this effect?

Particle model

Wave model

Electromagnetic model

Frequency model

Answers

Answer:

The answer is PARTICLE MODEL The person above ^^^ got the answer wrong, the correct answer really is Particle Model...

Thanks...

Answer:

Particle model

Explanation:

I am taking the test rnn

Flvs

what is magnetic induction ​

Answers

Answer:

The process of gaining or obtaining temporary magnetism in magnetic material due to the effect of magnet is called magnetic induction.

Answer:

Hey buddy here is your answer:-Magnetic Induction is the process by which an object or material is magnitized by an external field...

Foodborne illness outbreaks can be caused by microorganisms such as bacteria, viruses, or parasites. Determine whether each outbreak was caused by bacteria, viruses, or parasites.

a. A foodservice worker who doesn't wash his hands after handling contaminated seafood causes highly contagious tulike symptoms for passengers on a cruise ship
b. Raw oysters contaminated with Vibrio vulnicus.
c. An infected foodservice handler touches raw vegetables for a salad and transfers the condition that causes jaundice and liver damage to the customer who ordered the salad
d. A broken water main in a port town contaminates a boat's entre water supply with Cryptosporidium.
e. Prepackaged lettuce contaminated with Salmonella.
f. A broken meat thermometer ends up causing dinner guests to eat an undercooked pork roast infected with Thichinella spiralis.

Answers

Answer:

a. Undefined  

b. Bacteria

c. Viruses

d. Parasite

e. Bacteria

f. Parasite

Explanation:

In the first case is imperative to obtain more information in order to determine the causes of this contagious disease (contaminated seafood may be associated with different types of infections).

Vibrio vulnificus is a Gram-negative pathogenic bacterium associated with the consumption of contaminated oysters. V. vulnificus causes gastroenteritis, necrotizing infections and invasive sepsis.  

Jaundice is a condition caused by hepatitis A, B and E viruses, it is a disease associated with poor liver function and the destruction of red blood cells.  

Cryptosporidium parvum is a protist parasite (Phylum Apicomplexa) that causes the diarrheal disease cryptosporidiosis. C. parvum parasite is present in contaminated foods and water.

Salmonella enterica is a Gram-negative bacterium transmitted by eating contaminated foods, which causes severe diarrhea, fever and abdominal pain. Salmonella infection may also cause inflammatory diseases and dehydration.

Thichinella spiralis is a parasitic nematode that causes the trichinosis, a disease where larvae migrate to muscle, thereby producing muscle pains and serious pathologies. Trichinosis is caused by eating undercooked meat from contaminated animals.

Other Questions
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