g A rare genetic disease arises from mutations in subunits of TAP (TAP1 or TAP2). Individuals with this disease are susceptible to recurrent infections. What effects would you expect from this mutation

Answers

Answer 1

Explanation:

A rare genetic diseasearises from mutations in subunits of TAP (TAP 1 or TAP 2). The individuals with this disease are susceptable to recurrent infections.

The efforts could be expected from this mutation- MHC class II molecules will not be loaded with peptides, so CD8+ T cells cannot be activated. MHC class I molecules will not be loaded with peptides, so CD4+T cells cannot be activated MHC class I molecules will not be loaded with peptides, so CD8+T cells without be activated.


Related Questions

The correct air track for a human respiratory system is
A.
-
B.
trachea - bronchus - bronchiole alveoli
trachea - bronchiole - bronchus alveoli
bronchus -
trachea
alveoli
bronchiole
trachea alveoli bronchus
bronchiole
С.
u
D.​

Answers

Answer: Air enters through the nose (and sometimes the mouth), moves through the nasal cavity, the pharynx, the larynx, enters the trachea, moves through the bronchi and bronchioles till the alveoli.

Explanation:The pathway of air in the respiratory system starts with the external organs of the nose and mouth.

Nose: Air is inhaled through the nostrils (and sometimes through the mouth) where it is filtered by the hairs and cilia to remove dust particles and moistened. The nasal cavity also moderates the temperature of the inhaled air.

Pharynx: This is a common passage for food, water, and air. It leads from both the nose and the mouth and leads to both the trachea (windpipe) and the oesophagus (foodpipe).

Larynx: This is the voice box situated just over the trachea and has a flap called the epiglottis which closes during swallowing to prevent food from entering the trachea and opens during breathing.

Trachea: Air now enters the windpipe which is situated behind the sternum (breastbone) and between the two lungs.

Bronchus: From the trachea, two bronchi (one bronchus for each lung) enter the lungs and divide and subdivide into secondary and tertiary bronchi, getting narrower as they proceed into the lung.

Bronchioles: The tertiary bronchi branch into fine tubules called bronchioles, the last passageways for air.

Alveoli:. Air ends its pathway in the alveoli (sing. alveolus) which are tiny sacs with very fine singe-celled walls. These alveoli are surrounded by capillaries that connect the pulmonary arteries and veins and that enable transfer of oxygen and carbon dioxide.

The precursor of EGP is translated from a transcript that has had one non templated nucleotide added to the open reading frame. This change does not create or eliminate a stop codon. Compared with the protein sGP, which is produced from the unedited transcript, EGP most likely has the same primary:

Answers

Answer:

Explanation:

It was added somewhere in the middle. Since this is a frameshift, everything downwind of the addition will most likely be different.

The question is basically asking, if you change everything from the middle to the end of an amino acid sequence, which end changes and which end would remain the same?

It basically asks, when amino acids are assembled into proteins, are they built from the amino to the acid direction, or the acid to the amino direction?

The answer is that amino acid sequences are always assembled N to C, much like nucleotide sequences are built 5 to 3.

What are the student’s observations and inferences before he starts his investigation?

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Answer:

Hypothesis. A Hypothesis is an estimation of what might happen and the student's observation before moving on to investigate.

Importances of bacteria to humans​

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Answer:

Bacteria are very important to humans, both for good and for bad, due to their chemical effects and the role they play in spreading disease. In their beneficial effect, some bact

Some bacteria are used for the production of antibiotics which is useful to human

Select the statement about human impact on the environment that is FALSE. The number of humans engaging in a specific activity impacts the severity of the issue. Damaging the environment threatens human and ecosystem health. Pesticide and fertilizer use by humans is particularly damaging to the environment. Urban growth leads to increased waste, which leads to climate change.

Answers

Answer:

the answer is should be True

A suspension of yeast cells is being grown under anaerobic conditions such that glucose is metabolized to ethanol and carbon dioxide. An inhibitor of alcohol dehydrogenase is added to the suspension, the cells rapidly die. Explain.

Answers

Answer:

The correct answer is - NAD needed to keep glycolysis going is not being recycled so the entire process is shut down and no ATP is produced

Explanation:

Alcohol dehydrogenase plays role in metabolizing the bulk of ethanol consumed as part of the diet and their activities contribute to the rate of ethanol elimination from the body.

Inhibitor of this zinc enzyme prevents it to perform its function which results in NADH generated during anaerobic conditions glycolysis cannot be recycled back to NAD+, So the ATP production pf anaerobic condition through glycolysis cannot be maintained.

how does a viral immunization help prevent disease

Answers

Answer:

When people get vaccinated they there will be less change of transfer of communicable diseases

After fertilization occurs, the zygote undergoes cleavage and gets converted into 2,4,8 and subsequently a 16 celled stage known as morala. Thereafter certain changes occur in the morula and a blastocyst is formed. The blastocyst then gets implanted in the wall of the uterus.
A.3days

b. 6 days

c 10 days

d 14 days

Answers

Answer:

B. 6 days

Explanation:

I don't know a proper explanation, but overall it takes approx 6 days for the blastocyst to get implanted in the wall of the uterus.

How does temperature and concentration of monounsaturated phospholipids change the rate at which molecules permeate the plasma membrane? Does this change occur equally for low permeability ions the way and large molecules as it does for gasses and high permeability molecules?

Describe the way that enzymes increase the rate of chemical reactions in the cell. What other factors related to enzymes can increase or decrease this rate and why?

Answers

Answer:

я не знаю ответа извините

Explanation:

The biological classification of organisms is called taxonomy. Based on your own investigation, discuss the importance of taxonomy in biological research.

Answers

Answer:

mark me as brainliest

Explanation:

It helps to ascertain the number of living beings on Earth. More than one million of species of plants and animals have been discovered and classified so far. It aims to classify the living organisms. Millions of organisms are classified scientifically in categories, which helps to have a better understanding

The theory and practice of characterizing, naming, and classifying living things is known as taxonomy. Such research is critical for a basic knowledge of biodiversity and its preservation.

What is the importance of taxonomy in biological research?

Taxonomy is important because:

It aids in estimating the number of living beings on the planet. nearly one million plant and animal species have been identified and classified till date.Its goal is to classify living things. Thousands of creatures are scientifically divided into categories, which aids in understanding.It aids our understanding of the characteristics seen in plants and animals.It depicts the physical development in chronological order.It provides an overview of the local fauna and flora, which aids in the identification of endemic species.

learn more about taxonomy here:

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Is cell division a continuous process?

Illustrate with an example

Answers

Answer:

Cell division is the means of reproduction in unicellular organisms whereas it is the means of tissue growth and maintenance in multicellular organisms. ... In adults, cell divisions are involved in renewing old tissues rather than growth.,ya it is continuously processing

.1.2 The type of control shown in the diagram is known as

Answers

Answer:

which diagram

Explanation:

I hope you understand

The CT reveals several issues with the cranial structure, one of which might be in the cribriform plate but the image isn't well defined. What non-invasive test can you do to test if the cribriform plate is severely damaged? Why?

Answers

The non-invasive test that can be used to test if the cribriform plate is severely damaged is called the pledget study.

CRIBRIFORM PLATE is the part of the ethmoid bone that forms the nasal cavity.

The olfactory nerve which is part of the cranial nerves passes through the small opening found in the cribriform plate.

A damage to the cribriform plate leads to cerebrospinal fluid (CSF) leak which usually comes out from the nose and ears.

Therefore to test if the cribriform plate is severely damaged, the pledget study is performed.

Pledget study is a non-invasive method of diagnosing a CSF leak.

To perform this test,

Cotton pads called Pledgets are placed in the nostrils.If the leaking fluid contains CSF it will be detected.

The presence of CSF shows that there is damage to the cribriform plate.

This method is non invasive because it doesn't require the breaking or opening of any part of the body.

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In this diagram of a long bone, which type of bone marking is circled? anatomical drawing of a long bone showing the internal structure, with the point where the blood vessels enter circled

Answers

Answer:

the answer is osteon

Explanation:

List some Characteristic of fruits.​

Answers

Answer:

Quality factors for fruits include the following— maturity, firmness, the uniformity of size and shape, the absence of defects, skin and flesh color. Many of the same quality factors are described for vegetables, with the addition of texture-related attributes such as turgidity, toughness, and tenderness.

Whats bigger, fungi or virus?

Answers

Answer:

fungi

Explanation:

bcuz it is plant-like organism with lack of chlorophyll

PLEASE HELP FAST PLEASE ASAP HURRY

Answers

Answer:

A number is a correct answer

Nguyên nhân gây bệnh quáng gà ở người là do:đâu

Answers

Answer:

nearsightedness, or blurred vision when looking at faraway objects cataracts, or clouding of the eye's lens retinitis pigmentosa

Explanation:

Which interaction involves only one of Earth’s spheres?

Plant roots take in water from the soil.
Plants take in carbon dioxide from the air.
During photosynthesis, plants make food and release oxygen into the air.
Energy stored in plants is transferred to humans and animals that eat them.Which property of soil depends on the size of particles?

color
odor
temperature
texture

Answers

Answer:

Energy stored in plants is transferred to humans and animals that eat them

Explanation:

An increase in the biodiversity of an ecosystem leads to an increase in its productivity.

True
False

Answers

Answer:

true

Explanation:

The sodium-potassium pump does not do which of the following actions?
-Moves sodium molecules against their concentration gradient into the cell
using ATP.
-Moves sodium molecules against their concentration gradient out of the cell
using ATP.
-Maintains the cell's physiological needs by establishing an electrochemical
gradient.
-Moves potassium molecules against their concentration gradient into the cell
using ATP.

Answers

The sodium-potassium pump does not allow the movement of sodium molecules against their concentration gradient into the cell  with the use of ATP molecules.

In sodium-potassium pump, the sodium moves outside the cell whereas potassium moves inside the cell with the help of using ATP molecules. The sodium-potassium pump maintains the gradient of higher concentration of sodium extracellularly means outside the cell and a higher level of potassium intracellularly means inside the cell. This process is done only in the presence of ATP molecules that provides a force for the movement of sodium and potassium so we can conclude that no movement of sodium occur inside the cell in the sodium-potassium pump.

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Answer: Moves sodium molecules against their concentration gradient INTO the cell using ATP.

Explanation:

The sodium-potassium pump moves sodium molecules against their concentration gradient out of the cell and moves potassium molecules against their concentration gradient into the cell. It also helps to regulate internal physiological needs through gradients. However, it doesn’t move sodium ions into the cell—that occurs through passive transport.

PENN


Which of the following correctly lists functions o
proteins?
transporting substances, creating proteins,
and fighting disease
being the blueprints for life and the bases of
heredity
providing structure, regulating cell processes
and creating movement
O sending messages, providing structure, a
creating proteins

Answers

Answer:

please follow me

Explanation:

providing structure, regulating cell process and creating movement.

Help meeee!!!!
Why is it necessary to check total aerobic microorganisms in microbiological quality control but not to test total anaerobic microorganisms?

Answers

Answer:

While many microbes are harmless to humans, others can cause serious problems. They can spoil food, introduce toxins, cause disease and lead to a host of other problems. The importance of microbiological testing is to quickly identify these contaminants and treat them before they do irreversible damage.

Explanation:

Aerobic bacteria are bacteria that can grow and live when oxygen is present.

what is osmolarity of mammalian urine?​

Answers

Answer:

The osmolarity of mammalian urine may vary over time. The osmolarity of mammalian urine varies little between species. Mammalian urine is always hyperosmotic to blood. The osmolarity of mammalian urine may vary over time.

Explanation:

I hope it will help you

prove that Sin^6 ϴ-cos^6ϴ=(2Sin^2ϴ-1)(cos^2ϴ+sin^4ϴ) please sove step by step with language it is opt maths question ​ ​

Answers

Using basic identities in trigonometry....

In biological systems, there are several membrane transport systems responsible for the passage of ions like Na+ and K+.

a. True
b. False

Answers

Answer:

The correct answer is: a. True.

Explanation:

There are several membrane transport systems responsible for the passage of ions like Na+ and K+.

Cell membranes are semipermeable, which means they can regulate which molecules may and cannot flow through them. Some molecules may simply drift in and out of a cell (this is called simple diffusion), while others require specific structures to enter and exit (this type of diffusion is called facilitated diffusion), and still, others require an energy boost to pass the cell membrane (this is known as active transport).

Both simple diffusion and facilitated diffusion are types of passive transport: they happen without the energy boost that ATP gives, unlike active transport.

In passive transport, molecules follow their chemical gradients and travel through the most concentrated compartment to the less concentrated one to equal the concentrations. In active transport, on the other hand, the cell makes an effort to enter or exit ions against their chemical gradients and this is done particularly to maintain said gradients (they are required for the correct functioning of the cell).

Sodium and Potassium are two of the most important ions when it comes to maintaining these gradients: sodium is very concentrated in the outside of the cells (the extracellular compartment), while potassium is highly concentrated in the intracellular compartment. These differences in concentrations are maintained thanks to the Na+/K+ pump, a form of active transport. Apart from the Na+/K+ pump, these ions go through the membrane through passive transport as well, without requiring energy.

Why DNA synthesis is faster than RNA synthesis?is there any advantage of being faster?

Answers

Answer:

Explanation:

I read it's has to do with the amount of nucleic acid that must be synthesized. RNAs are tiny compared to DNA, so there is little selection pressure for speed. Also, multiple RNA polymerases can initiate simultaneously, effectively increasing the synthesis rate

Answer:An obstacle to the triviality of the first issue includes the fact that DNA polymerase replicates DNA at a rate of 10-15 times faster than RNA polymerase transcribes DNA so that these enzymes inevitably collide if they attempt to function concurrently and co-directionally

Explanation:

At any given instant, only a fraction of the genome (total DNA) is being transcribed. Consequently, speed is not necessary.

For both clinical and cosmetic reasons, plastic surgeons inject substances into connective tissue underlying the skin epidermis. This plumps up areas deficient in soft tissue, and is used to reduce surgical scars or wrinkles, for example. Which normal connective tissue components are good candidates to be injected as fillers in this type of procedure

Answers

Answer:B.) collagen

C.) glycosaminoglycan

Explanation:

Enzymes secreted by the lining of the stomach to aid digestion are specially designed to function under what conditions?
a. Low temperature
b. Low pH
c. High pressure
d. High pH

Answers

Answer:

A, Low tempature

Explanation:

Im sure you know what denaturing is by now, and denaturing of an enzyme happens when it gets too hot, so Low tempature is the answer, hope this helps, mark me a brainliest if you can

is mucous an enzyme or harmone​

Answers

Answer:

It's an Enzyme.

Explanation:

It is a viscous colloid containing inorganic salts, antimicrobial enzymes (such as lysozymes), immunoglobulins (especially IgA), and glycoproteins such as lactoferrin and mucins, which are produced by goblet cells in the mucous membranes and submucosal glands.

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The idea of an "American Identity" has evolved dramatically since our nation's creation.1. What is your perspective of the American identity? There is no "correct" answer, but your response should be thoughtful.2. How would you describe the culture of the United States? Think about this on a macro (entire country as a culture) scale and a micro (your community's culture) scale.3. Think of a book you've read or a movie you've seen that exhibits this perspective. In what way does it reflect the American identity? Angelicas bouquet of dozen roses contains 5 white roses. The rest of the roses. What fraction of the bouquet is pink? There are 12 roses in a dozen explain the relationship between small particle aerosols and areas od dense population Which of the following statements about condoms is true?A. Condoms eliminate any risk of contracting sexually transmitted infection (STIs) that are transmitted through bodily fluids.B. Condoms provide less protection against STIs spread through skin-to-skin contact, like human papillomavirus (genital warts), genital herpes, and syphilis.C. Condoms remove the risk of contracting HIV, so if you are using condoms properly, there is no need to use additional prevention methods.D. Condoms will greatly reduce any risk from STIs spread through skin-to-skin contact, like human papillomavirus (genital warts), genital herpes, and syphilis. Given: mV=103, mVRT=71, RS VU Find: mTRS, mU Select all that apply.Which items are properties of bases?soapysourbitterslickskin damagePlease what is tue cause of upthrust ? I need help for this question 3 so can anyone help me please Write the equation of the line with a slope of 4 that contains the point (5, 8). Why are the divisibility rules for 2, 3, and 5 very useful for determining prime and composite numbers1. They are the smallest odd numbers2. They add up to 103. They are prime numbers with nice divisibility rules4. They multiply to 305. They can be multiplied together to make every number 1. If your vehicle breaks down while moving, pull off the road as far asten feetthe shoulderthe ditchpossible HELP PLS HELP MEEEEE IM FAILING PYTHAGOREAN THEOREM 11. Cmo se llama y dnde vive? 12. Cuntos aos tiene y tiene hermanos/-as? 13. Cul es su pasatiempo favorito? 14. Quin es su amigo/-a mejor y por qu? 15. Qu va a hacer hoy? 16. Tiene una mascota? 17. Qu har despus de graduarse de Penn Foster y por qu? 18. Adnde ir maana? 19. Qu hizo ayer? 20. Adnde ha viajado recientemente y con quin fue Where (be).....your father now? Please answer this!! Which compromise between the Church and the Holy Roman Empire resulted from the Concordat of Worms? K. Johnson, Inc.'s managers want to evaluate the firm's prior-year performance in terms of its contribution to shareholder value. This past year, the firm earned an operating income return on investment of 12 percent, compared to an industry norm of 11 percent. It has been estimated that the firm's investors have an opportunity cost on their funds of 15 percent, which is the same as the firm's overall cost of capital. The firm's total assets for the year were exist100 million. Required:a. Compute the amount of economic value created or destroyed by the firm.b. How does your finding support or fail to support what you would conclude using ratio analysis to evaluate the firm's performance? The MLH1 protein dimerizes with the PMS2 protein to form a complex that is involved in the correction of errors of DNA replication. Loss-of-function mutations in the genes that encode for these proteins increase the incidence of colon cancer. Which type of DNA error would be repaired by the activity of this complex I am not following you. Change into passive. Express each of these percentages as a fraction158%solution for class 7