Answer:
The nurse should closely monitor the client for signs and symptoms of infection, such as fever, chills, sore throat, and other signs of infection. The nurse should also monitor for signs of bleeding or bruising, as immunosuppressive drugs can increase the risk of bleeding. The nurse should also monitor for signs of organ rejection, such as skin rash, abdominal pain, and fatigue.
Explanation:
You are given a novel drug that inhibits the activity of a GPCR kinase (GRK) specific for GPCR's that bind adrenaline (epinephrine). You know that adrenaline increases heart rate and activates adenylyl cyclase leading to breakdown of glycogen in muscle. You inject two rats. Rat #1 is given an injection of the novel drug followed by adrenaline, while rat #2 is injected with adrenaline only. Which of the following would you find when you analyze the rats 5 min after injection of adrenaline? Rat # 1 has increased glycogen and increased cAMP in muscle, and increased heart rate relative to Rat #2 O Rat # 1 has decreased glycogen and increased cAMP in muscle, and increased heart rate relative to Rat #2 O Rat # 1 has decreased glycogen and increased cAMP in muscle, and decreased heart rate relative to Rat #2 Rat # 1 has decreased glycogen and decreased cAMP in muscle, and decreased heart rate relative to Rat #2 O No difference in levels of glycogen and cAMP in muscle, and heart rate in rat #1 compared to rat #2
Rat # 1 has decreased glycogen and increased cAMP in muscle, and increased heart rate relative to Rat #2.
What is adrenaline?Adrenaline is a hormone that increases heart rate and activates adenylyl cyclase resulting in the breakdown of glycogen in muscle. G protein-coupled receptor kinases (GRKs) phosphorylate and inactivate activated G protein-coupled receptors (GPCRs).
GPCR kinase inhibitors have been identified and designed to selectively inhibit GRKs that regulate specific GPCRs. It has been discovered that GRK2 inhibition could be used to treat heart failure because it improved cardiac contractile function and reduced mortality. The drug used in the experiment inhibits the GPCR kinase (GRK) specific for GPCR's that bind adrenaline (epinephrine).
The inhibition of GRK prevents the deactivation of the receptor and thus increases the signal sent downstream. Rat #1 is given an injection of the novel drug followed by adrenaline, while rat #2 is injected with adrenaline only. In rat #1, the novel drug inhibits the activity of the GRK. As a result, adrenaline signaling will be amplified in the animal, which results in a decrease in glycogen levels. The rate of glycogenolysis is increased in rat #1 due to the inhibition of the GRK, this increases cAMP.
The increase in cAMP levels in rat #1 is due to the inhibition of the GRK. The increase in cAMP levels will increase the heart rate in rat #1 relative to rat #2.In rat #2, cAMP and glycogen levels increase after adrenaline is administered, and the heart rate increases as well. However, the increase in the rate of glycogenolysis and cAMP production will be less in rat #2 than in rat #1, resulting in a lower heart rate relative to rat #1.
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On hand is 17.5mg/6ml of heparin. The physician orders 35mg how many mL with the MA administer
The medical assistant should administer 12 ml of the heparin solution to deliver 35 mg of heparin.
To administer 35mg of heparin using the concentration of 17.5mg/6ml, we can use a simple proportion:
17.5mg/6ml = 35mg/x ml
Cross-multiplying, we get:
17.5mg * x ml = 35mg * 6ml
Simplifying, we get:
x ml = (35mg * 6ml) / 17.5mg
x ml = 12ml (rounded to the nearest tenth)
Therefore, the medical assistant should administer 12ml of the heparin solution to deliver 35mg of heparin.
What is heparin solution?
Heparin solution is a medication used to prevent and treat blood clots. It works by blocking the formation of blood clots and by preventing existing blood clots from growing larger. Heparin solution is usually administered by injection into a vein or under the skin. It is often used in hospital settings, such as during surgery or in patients who are immobilized for extended periods of time, to reduce the risk of blood clots forming. Heparin solution comes in various concentrations and is available by prescription only.
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Which of the following statements related to critical or semi-critical, or non-critical patient-care items is correct?A. Heat tolerant critical and semi-critical items must be sterilized by steam, unsaturated chemical vapor, or dry heat.B. Heat-sensitive critical items can be sterilized by ethylene oxide or by immersing them in liquid chemical germicides registered by the FDA as chemical sterilants.C. Non-critical items, when visibly soiled, must be disinfected with an EPA-registered hospital level intermediate-level disinfectant.D. All of the above are correct.
The correct statement among the following statements related to critical, or semi-critical, or non-critical patient-care items is: (A) heat tolerant critical and semi-critical items must be sterilized by steam, unsaturated chemical vapor, or dry heat.
Sterilization is a method used to destroy and remove all microbial life including highly resistant bacterial endospores. It is used in hospitals and other medical facilities to avoid the spread of dangerous diseases and infections. Among the given options, the correct statement related to critical or semi-critical, or non-critical patient-care items is that (A) heat-tolerant critical and semi-critical items must be sterilized by steam, unsaturated chemical vapor, or dry heat.
Option B is incorrect because heat-sensitive critical items cannot be sterilized by ethylene oxide or by immersing them in liquid chemical germicides registered by the FDA as chemical sterilants. They are sterilized by low-temperature hydrogen peroxide gas plasma, vaporized hydrogen peroxide, or ozone.
Option C is also incorrect because non-critical items, when visibly soiled, must be disinfected with an EPA-registered hospital-level low-level disinfectant but not an intermediate-level disinfectant. Disinfection is the process of killing harmful microorganisms using chemicals or physical agents.
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which action should the nurse associate with outcome identification and planning in the nursing process?
The nurse should associate the following action with outcome identification and planning in the nursing process: establishing client-centered goals and expected outcomes.
The nursing process is a methodical and cyclic approach to providing nursing care. The nursing process is built on the foundation of a patient-centered philosophy that emphasizes the importance of the individual and their medical needs. It involves a series of interrelated stages that are followed in order and in a systematic manner.
The five stages of the nursing process include assessment, diagnosis, outcome identification and planning, implementation, and evaluation.
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