The muscle weakness of myasthenia gravis results from loss of acetylcholine receptors in the end-plate membrane. the motor neuron action potential being too small to shock the muscle fibers. insufficient acetylcholine release from presynaptic vesicles. excessive acetylcholinesterase that destroys the neurotransmitter. All of the answers probably contribute to the muscle weakness.

Answers

Answer 1

Answer:

The correct answer is ''loss of acetylcholine receptors in the end-plate membrane.''

Explanation:

Myasthenia gravis represents a human autoimmune disease. The neuromuscular junction abnormalities that occur in this disease are due to antibody-mediated processes. A reduction in the number of functional acetylcholine receptors on the postsynaptic membrane was established to contribute to the physiological abnormalities of myasthenia gravis. The reduction in receptors is due to immunological alterations directed against the acetylcholine receptor. Normally, when acetylcholine binds to its receptor, it opens allowing the rapid entry of cations, especially sodium. With this, the depolarization of the postsynaptic region of the muscle fiber occurs. Although acetylcholine is normally released in myasthenia gravis, it is not capable of causing an action potential in the muscle sufficient to initiate or weaken contraction. In patients with myasthenia gravis, failure to activate muscles is responsible for myasthenic fatigue. Most patients have elevated serum titers of antireceptor antibodies, which in turn accelerate receptor degradation.


Related Questions

Why are
there no gram-positive archaea species, but there are gram-positive
bacteria species?

Answers

Answer:

There are no gram positive archaea because archaea lack peptidoglycan in their cell walls, meaning that the archaeic cell walls are more similar to gram negative bacterial walls, although they do show a greater variety of cell wall types.

EXPLANATION

Bacteria can be divided into gram-positive bacteria and gram-negative bacteria because of their cell wall composition.   The cell wall of gram-positive bacteria is made up of peptidoglycan which retains crystal violet stain and appears purple in color under microscope. The cell wall of gram-negative bacteria has an outer layer of lipopolysaccharide which do not retain crystal violet color and appear pink.   The cell wall of archaea is not made up of peptidoglycan but is made up of pseudo-peptidoglycan, therefore, no gram-positive archaea species is present on the earth.

what is the main reason for using a data table to collect data?​

Answers

Answer:

the correct awnser is a to understand better

Answer:

the correct answer is a because tables make data easier to understand

Pls Answer it for 50 points pls What is arsenic???

Answers

Arsenic is natural element widely distributed in the earth's crust.

There are two forms of arsenic organic and inorganic.

Symbol: As

Electron configuration: [Ar] 3d¹⁰4s²4p³

Atomic number: 33

Atomic mass: 74.9216 u

Electronegativity: 2.18

Answered by Gauthmath must click thanks and mark brainliest

I Name the following: 1. It is the mechanism of inheritance of characters from the parental generation to the offspring.​

Answers

Answer:

yes

Explanation:

even with some characteristics it can be past down with out even being around said parent mostly things like habits example: being more likely to have a addiction to anything doesn't have to be bad substances it part of ur gene make up


•Differentiate between virus and viroids.​

Answers

Viruses (Virus particles or virions) are usually units consisting of nucleic acids and coat proteins called capsids.

Viroids consist only of RNA, i.e. they contain no protein at all. Except for a few cases, viruses are not surrounded by a membrane.

Answer:

Viruses (Virus particles or virions) are usually units consisting of nucleic acids and coat proteins called capsids. Viroids consist only of RNA, i.e. they contain no protein at all. Except for a few cases, viruses are not surrounded by a membrane.

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..nok nok tera bhai aaya

PLEASE HELP NEEDEDASAP

Answers

Answer:

My best guess would be the first option.

Explanation:

For example, when people began chopping down trees and making settlements in South America, fire ants started to move north in search for new homes. Eventually, they've became a huge problem to North America due to North America having no natural predators capable of eating these violent ants.

Answer:

Por ejemplo, cuando la gente comenzó a talar árboles y hacer asentamientos en América del Sur, las hormigas rojas comenzaron a moverse hacia el norte en busca de nuevos hogares. Con el tiempo, se han convertido en un gran problema para América del Norte debido a que América del Norte no tiene depredadores naturales capaces de comerse estas violentas hormigas.

GRACIAS

 

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Explanation:

We use electrical devices that produce motion, light, and sound. Which aspect of energy explains why these devices are possible?

Answers

Answer:

The suns energy or the solar energy

Explanation:

In the Avery, MacLeod, and McCarty experiment, the transforming extract from virulent bacteria was treated with DNase, RNase, or protease before being mixed with nonvirulent bacteria. The appropriate control for this experiment is to treat the transforming extract from heat-killed virulent bacteria with:

Answers

Answer:

Nothing

Explanation:

A. Control variables generally entail little or no system change. To see if the method worked, the researchers required a positive control in which the heat-killed virulent bacteria invariably transformed the non-virulent microorganisms. This positive control involves adding "nothing" to both the heat-killed virulent bacteria before mixing them with the non-virulent bacteria.

WHY ARE THE TROPHIC LEVELS AND ENERGY REPRESENTED IN THE FORM OF PYRAMIDS?

Answers

Answer:

An energy pyramid shows the distribution of energy among trophic levels. Producers use energy from sunlight to make food. Herbivores eat plants—the producers—to get energy. ... Each level above gets smaller, because as energy is lost as heat, there is less energy avail- able as food for organisms.

Does anyone know the answer for 1?

Answers

The correct answer of question number 1 is D. Sill

What is the effect of mutated GLMN Gene on the human body?

Answers

Answer:

A novel gene , glomulin (GLMN) in which 40 different mutation.

You are studying nuclear lamins and use recombinant DNA technology to alter the coding sequence of a nuclear lamin gene. The alteration you make creates a situation such that the gene now codes for a nuclear lamin protein that can no longer be phosphorylated when the nuclear envelope is broken down during mitosis. What do you predict would happen if the cell only had the altered nuclear lamin gene (and not the unaltered version)

Answers

Answer:

Nuclear lamins will no longer disassemble during mitosis

Explanation:

The nuclear lamina is a fibrillar network inside the nucleus of eukaryotic cells, between the inner nuclear membrane and the peripheral chromatin. Nuclear lamins (also called simply lamin proteins) are intermediate filament-type proteins and represent the major building blocks of the nuclear lamina. During mitosis, the nuclear lamina is disassembled by hyperphosphorylation of nuclear lamins and lamina-associated proteins. The protein responsible for phosphorylating nuclear lamins is p34cdc2, a protein kinase that has a key role in controlling cell cycle progression. In consequence, a mutant form of the nuclear lamin proteins that cannot be phosphorylated will no longer be able to disassemble during mitosis.

What is the powerhouse of the cell called?

Answers

Mitochondria is called the powerhouse of the cell.

Hope this helps! Have a great day :)

Mitochondria are known as the “powerhouse of the cell.”

Why is avian influenza (H5 N1) rarely transmitted from poultry to humans? Why is it is often lethal
in humans? Why is it rarely spread from person to person?

Answers

Answer:

Lacks the right key to unlock many cells.

Explanation:

Avian influenza (H5 N1) rarely transmitted from poultry to humans because it lacks the right key to unlock many cells in the upper respiratory tract so due to this action the virus is rarely transmitted to humans. Sometimes it is lethal to humans due to absence of antibodies for this type of virus. It is rarely spread from person to person due to inability to enters the other human body.


Which equation is most likely used to determine the acceleration from a velocity vs time graph?

Answers

Answer:

The equation/formula to find acceleration from a velocity time graph is....

     acceleration = velocity / time

Hope this helps!

The answer is acceleration = velocity/time let me know if this helps or not

Why is the unit of velocity called derived unit?​

Answers

Answer:

Because it is a vector quantity, it has a direction too such that derived unit is made up of two or more fundamental units. That is mere and second. That is why it is called as a derived unit as its unit is metres per second.

Hope this helps...Have a good day!!

what traits could a plant that it would help it grow better in space

Answers

LED lights shine above to give the plants the energy they need to grow, and expandable plastic walls provide protection for the leaves as they get taller. So far, astronauts have just grown red romaine lettuce

Answer:

LED lights shine above to give the plants the energy they need to grow, and expandable plastic walls provide protection for the leaves as they get taller. So far, astronauts have just grown red romaine lettuce, but in the future, they will grow cabbage and tomatoes with seeds from the next SpaceX delivery.

Explanation:

Please Mark me brainliest

how does baby get its shape in the womb of an woman?​

Answers

Answer:

Uterus (also called the womb): The uterus is a hollow, pear-shaped organ located in a woman's lower abdomen, between the bladder and the rectum, that sheds its lining each month during menstruation. When a fertilized egg (ovum) becomes implanted in the uterus, the baby develops there.

If new genetic variation in the experimental populations arose solely by spontaneous mutations, then the most effective process for subsequently increasing the prevalence of the beneficial mutations in the population over the course of generations is

Answers

Answer:

binary fission

Explanation:

Binary fission is the main type of reproduction of prokaryotic organisms. In binary fission, the prokaryotic cell first duplicates its DNA and then divides into two cells, each one receiving one complete DNA molecule. Since binary fission is a type of asexual reproduction, this process increases the prevalence of beneficial mutations in a bacterial population. Moreover, transduction refers to the process by which a virus transfers genetic information from one bacterium to another bacterium. Conjugation is also a sexual mode of transfer of DNA from a donor (F+) to a recipient (F−) bacterial cell by direct cell-to-cell contact. Finally, transformation refers to the transfer of genetic material by which bacteria take up exogenous DNA from the environment and integrate it in their genomes.

What is the correct structure of ATP? A. Ribose sugar, Adenine base, 3 Phosphate groups B. Triglyceride head, Ribose sugar, 3 fatty acids C. Ribose sugar, Phosphate group, Nitrogen Base D. Deoxy Ribsose sugar, Adenine base, 3 Phosphate groups

Answers

Answer:

The correct structure of ATP is

A. Ribose sugar, Adenine base, 3 Phosphate groups

Explanation:

The structure of ATP is a nucleotide, consisting of a nitrogenous base (adenine), a ribose sugar, and 3 serially bonded phosphate groups.

Individuals with a mutation in the gene for apolipoprotein B-100 produce very low levels of this protein, which is a component of LDL. How would accumulation of fat in the liver be affected and would this result in hypercholesterolemia or hypercholesterolemia

Answers

Answer:

Fats would accumulate in the liver and the individual would show hypocholesterolemia

Explanation:

Familial hypercholesterolemia is a genetic disorder caused by a reduction and/or defect in the low-density lipoprotein (LDL) receptor. Moreover, apolipoprotein B is the unique protein component of LDL, which plays a critical role in lipid metabolism by binding the LDL receptor. Familial defective apolipoprotein B-100 refers to an inherited disorder associated with mutations of the apolipoprotein B-100 that leads to moderate or severe cases of hypercholesterolemia. Mutations in apolipoprotein B-100 are associated with a reduction in the binding capacity of LDL to the LDL receptor, thereby leading to hypercholesterolemia.

Which of these is the main cause of habitat fragmentation? O A. Reduction in genetic diversity O B. Migration of mammal species O C. Demand for land use O D. Extinction of bird species​

Answers

Answer:

C. Demand for land use

Explanation:

Habitat fragmentation usually occurs because of human activities such as new roads, parking lots, and housing developments. Organisms need their specific habitat for survival, and fragmentation is a leading threat to many terrestrial animals.

You look at a cell using a microscope. You see ribosomes and a nucleoid that has one circular chromosome and no surrounding membrane. You do not see any endoplasmic reticulum, mitochondria, Golgi or chloroplasts. From these observations you would conclude you were looking at Group of answer choices

Answers

A Prokaryotic Cell.

Mary likes sour foods, and she decided to eat a slice of lemon. As she bit down on the lemon, she felt an uncomfortable squeezing-type sensation in her cheek as one of her salivary glands emptied its secretions into her mouth. Which of the three pairs of salivary glands did she feel

Answers

She felt the parotid.

I'm 99% sure this is right lol

Pros and cons about lobsters not feeling pain…

Answers

Answer:

The pro of not feeling pain is not feeling pain and the con is pain help you survive like hot hand on stove if u don’t feel pain you probably won’t take your hands off and it can cause death and stuff (u probably know what I mean I hope)

Explanation:

What is one of the causes of mechanical weathering?

A. acid rain
B. oxidation
C. animal actions
D. carbon dioxide

Answers

C. animal actions

Others are chemical examples.

i think your answer might be animal actions

Differentiate between communicable and non-communicable diseases. Give one example of each​

Answers

Answer:

hope this helps helps you a lot

my handwriting is bad sorry for that bhai

Why do you think engineers working on the Venice Tide Barrier project are following the Engineering and Design Process?

A. A creative, effective solution an be developed
B. The Engineering and Design Process costs more time and money
C. It eliminates the need for creativity
D. Over time, there will be no need to brainstorm or test ideas

Answers

Answer:

Please correct me if I’m wrong but I believe it’s cause it’s A

Explanation:

sorry If I answered your question wrong I didn’t mean to I really tried

Answer:

listening the money by the drums

Explanation:

Cells in the human body carry out different functions. Which cells help the body fight off diseases and remain healthy? Choose the two that apply.

Answers

Phagocytes and lymphocytes

On your first research mission you make an amazing discovery by finding a new species living in the hostile environment of the Sahara desert. After observing it carefully you determine that it is not an autotroph, it is multicellular, and it does not contain any chitin. What is the best classification for it

Answers

Answer:

Animalia

Explanation:

A multicellular organism is an organism composed of two or more cells. Multicellular organisms include animals (i.e., organisms from kingdom Animalia), plants, and most fungi. Moreover, an autotroph is a living organism that can produce its own food by using materials from inorganic sources (e.g., water, carbon dioxide, etc); whereas a heterotroph is an organism that cannot produce its own food and thereby needs to eat other organisms, like plants or animals, to survive. Multicellular autotrophs are typically plants; whereas multicellular heterotrophs include all animals, fungi and some parasitic plants. Finally, chitin is a polysaccharide (polymer) of N-acetylglucosamine, which is found in the cell wall of fungi, as well as in the exoskeleton of some animal groups such as, for example, insects, crustaceans, etc.

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