The immunoglobulin light chain does not have a D segment. In humans, there are two different possible light chain proteins, termed kappa and lambda. Assume that there are 35 V segments and 5 J segments in the human kappa light chain region, and there are 30 V segments and 4 J segments in the human lambda light chain region. How many possible light chain genes can be created from these different segments, simply due to combinatorial diversity

Answers

Answer 1

Answer:

295  

Explanation:

Antibodies (also known as immunoglobulins) are immune system-related proteins that circulate in the bloodstream in order to recognize pathogenic harmful substances (antigens) and neutralize them. An antibody consists of two immunoglobulin heavy chains and two immunoglobulin light chains. There are two types of immunoglobulin light chains: 1-the kappa (κ) light chain, which is encoded by the immunoglobulin κ locus; and 2-the lambda (λ) light chain, which is encoded by the immunoglobulin λ locus. The immunoglobulin light chain is a multidomain protein composed of two domains: 1- the N-terminal variable (V) domain and 2-the C-terminal constant (C) domain. V(D)J recombination is a type of somatic rearrangement process by which T and B cells can assemble different gene segments, which are referred to as variable (V), diversity (D) and joining (J) gene segments. In the question above the number of possible genomic recombination events between immunoglobulin gene segments can be calculated as >> (5 x 35) + (4 x 30) = 295.


Related Questions

What is Alzheimer's disease??​

Answers

Answer:

Alzheimer's disease is a progressive neurologic disorder that causes the brain to shrink (atrophy) and brain cells to die.

Explanation:

Hope it is helpful.

Thankyou

Answer:

Alzhimers disease is a progressive neurologic disorder that causes the brain to shrink and brain cells to die . Alzhimers disease is the most common causes of dementia - a continious decline in thinking behavorial and social skills that affects persons ability to function indepedently .

The neurons that carry from the brain to the muscle are called ?

Answers

Answer:

Motor Neurons

Answer:

The neurons that carry messages to the muscles are called motor neurons.

Whose argument is stronger regarding the SAC curves and the LAC​ curve? A. The draftsman since the lowest point on each SAC curve will have a horizontal tangent line which only occurs at the lowest point on the LAC. B. Jacob Viner since the SAC curves can be adjusted slightly and still keep their​ U-shape in a way that makes their lowest points end up on the LAC curve. C. Jacob Viner since the​ long-run average cost curve must be composed of the lowest points on any individual​ short-run average cost curve. D. The draftsman​ since, while it is true that the points of tangency of the SAC curves with the LAC curve are at each SAC​ curve's minimum, it is impossible to illustrate it accurately.

Answers

NB: This is a business question, not biology.

Answer:

SAC (Short-run Average Cost) and LAC (Long-run Average Cost)

The stronger argument regarding the SAC (Short-run Average Cost) curves and the LAC (Long-run Average Cost) curves is:

A. The draftsman since the lowest point on each SAC curve will have a horizontal tangent line which only occurs at the lowest point on the LAC.

Explanation:

The costs of all factors of production become variable in the long run.  But in the short-run, some costs are variable, and some are fixed.  When the producer starts operating over the long run period, it can then operate without the constraints imposed by the presence of the fixed-cost factors. Therefore, in the long run, the average cost (LAC) is equal to the short-run average cost (SAC) because there is an unconstrained minimum average cost at all output levels.

Which trait is totally determined by genes

Answers

Answer:

hair color is determined by genetics

Explanation:

Eye color, hair texture or color, unattached earlobes or attached.

Which is another name for observation?

Answers

Answer:

I would say hypothesis  is what we use for science as a guess, but also monitoring is a good one.

Explanation:

Another name for observation is inspection.

What is the correct order of the levels of organization in animals from smallest to largest?​

Answers

Answer:

Molecules, cells, tissue, organ, organ system, organism, population, community, ecosystem, and biosphere are in the correct order of the organization's levels.

Explanation:

Molecule: Atoms, the smallest unit of chemical elements are built up of molecules. You can find it in any matter, whether it lives or not. The most fundamental structures of biological creatures are molecules. Biochemistry and molecular biology are two biological fields focused on this level.

Cell: A cell is the basic unit of life. Two types of cells exist plant cells with a stiff cell wall consisting of cellulose molecules and animal cells with a flexible cell membrane. Cell biologists examine problems like metabolism and other structure and functional questions within and between cells.

Tissue: Tissue consists of cells working together to accomplish a goal. Some tissues include muscle, connective tissue, and neural tissue. Examples of biologists working at this level are histologists.

Organ: An organ is a tissue system that works at bigger scales together to perform specified work in the body of an animal. Brain, heart, and lungs are examples of organs. Anatomy is an example of a specialty in biology which concerns this level.

Organ system: An organ system is a group of bodies that work together to fulfill certain activities of the body. Air systems are used to inhale oxygen and release carbon dioxide in animals, for example, by the lungs, respiratory tract, and muscles. The function of the corpus when working jointly is studied by physiologists. Although physiologists can work at any level, they commonly address queries about organ systems.

Organism: An organism is an autonomous and recognized person. The organisms might be single-cell or multi-cell organisms consisting of organisms and organ systems, as well as bacteria, amiable, or creatures. An example of a multi-cellular organism is a human being.

Câu 4: Nghiên cứu về lạm phát nằm trong đối tượng của…
a. kinh tế học vi mô.
b. kinh tế học vĩ mô.
c. kinh tế học thực chứng.
d. kinh tế học chuẩn tắc.

Answers

Answer:

Explanation:

B. Kinh tế học vĩ mô


The layer of soil that contains the most organic material is called the
a. A
C C
b. B
d D

Answers

Answer:

That layer is called the a horizon, so the answer is A.

Explanation:

hi,I was feeling so bored so I give this question What is climate change and what r the causes of climate change?​

Answers

Answer:

Climate change is the global phenomenon of climate transformation characterized by the changes in the usual climate of the planet (regarding temperature, precipitation, and wind) that are especially caused by human activities

Humans are increasingly influencing the climate and the earth's temperature by burning fossil fuels, cutting down forests and farming livestock. This adds enormous amounts of greenhouse gases to those naturally occurring in the atmosphere, increasing the greenhouse effect and global warming. Humanity’s increased use of fossil fuels – such as coal, oil and gas to generate electricity, run cars and other forms of transport, and power manufacturing and industry

Deforestation – because living trees absorb and store carbon dioxide

Increasingly intensive agriculture – which emits greenhouse gases like methane and nitrous oxide

Why might an individual with AIDS have difficulty fighting off otherwise harmless infections? please answer!! last question I have!!! ​

Answers

Answer:

The HIV virus that causes AIDS kills T-cells. T-cells are responsible for fighting off infections. So someone with AIDS has a reduced number of T-cells and are unable to fight off infections that are harmless to other individuals.

8.Explain how is small intestine designed to absorb digested food.
9. Write two differences between the nutrition in amoeba and human beings.
10. Fungus can be harmful and useful. Give an example showing both of these traits of fungus.

Answers

Answer:

10. Fungus are useful as they act as decomposers and decompose the dead things. Fungus are harmful as they can decompose fruits, grains and plants etc.

Tell me how bacteria make their energy and other chemical products.

Answers

Answer:

Bacteria can obtain energy and nutrients by performing photosynthesis, decomposing dead organisms and wastes, or breaking down chemical compounds. Bacteria can obtain energy and nutrients by establishing close relationships with other organisms, including mutualistic and parasitic relationships.

Explanation:

I hope it helps! Please mark my answer as bräinliest! Thank You!

Which is the main light-absorbing pigment for photosynthesis?
O carotene
O chlorophyll
O hemoglobin
O anthocyanin

Answers

Answer:

Chlorophyll

Explanation:

Chlorophyll, the primary pigment used in photosynthesis, reflects green light and absorbs red and blue light most strongly.

In plants, photosynthesis takes place in chloroplasts, which contain the chlorophyll.

Answer:

B) Chlorophyll

Explanation:

The chloroplasts, which contain the green pigment chlorophyll, are where photosynthesis takes place. Chlorophyll is the pigment that gives plants their distinctive color. It works by collecting the energy in the sunlight that strikes the plant. Because grass requires photosnthesis to create glucose, which is required for growth inside the grass, photosynthesis is critical to life on Earth. As a result, creatures that eat the grass get energy, and so on. As a result, photosynthesis is the mechanism through which energy is introduced into an environment.

OAmalOHopeO

Biomagnification results in higher amounts of toxic substances for organisms on the food chain
True
False

Answers

Answer:

Biomagnification results is higher in amount of toxin substances so the answer is true

Explanation:

2Which term describes the two groups of plants that do not need water to reproduce?
A. spermatophytes
B. cotyledons
C. embryophytes
D. Paleozoic plants

Answers

Answer:

A

Explanation:

.............................spermatophytes...........................

Which answer option below describes the best way to increase the accuracy of a
confidence interval calculation?

Answers

The answer is c but this has to be twenty characters long

The accuracy of a confidence interval calculation can be increased from  95% to 99%.

Thus, option C is correct.

What is confidence interval?

A confidence interval contain a population parameter in a specified proportion of the time, which can be computed using the given confidence level from a limitless level of individual sample.

The proportion of the range consists of the true value of the factor that will be identical to the confidence level.

In most of the confidence interval examples, the confidence level chosen is 95%. and it can be raise up to 99%.

It cannot estimate the plausible values of the unknown parameter of the population.

Two types of confidence interval observed such as accuracy which is defined based on whether the confidence interval contains the true population parameter or not.

Secondly, the precision defined in terms of the width of a confidence interval.

Hence, option C is correct.

Learn more about confidence interval, here:

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Ġ Surface area te volume ratio plays a vital role in À. growth rate of organisms B. exchange of materials between organisms and their environment C. the life-span of organisms D. efficiency of various systems in organisms

Answers

Answer:

Exchange of materials between organisms and their environment

Explanation:

Writing Assignment
One of the main functions of connective tissue is to integrate
organs and organ systems in the body, Discuss how blood
fulfills this role.

Answers

Answer:

Major functions of connective tissue include: 1) binding and supporting, 2) protecting, 3) insulating, 4) storing reserve fuel, and 5) transporting substances within the body .Blood integrates organs and organ systems by transporting and exchanging fluid with various organs and organ system to allow them to function and work properly allowing the organism to survive

Below is an image of a nucleus before it divides via meiosis. The chromosomes shown in red are from the female parent, and the chromosomes
in blue are from the male parent. Predict the gametes that can be created from this organism and explain the reason these different gametes are
possible.

Answers

Answer:

I predict that the gametes will be unique from their parents.

Explanation:

I predict that the chromosomes will pair up, with each pair having a red chromosome and a blue chromosome, then they'll cross over and exchange similar genetic information with each other. I think this because variety is important for any species for survival.

ason Kimble's study of the Archaea in Snowy River in Fort Stanton Cave showed that Archaea play an important role in __________.

Answers

Answer:

Ecosystem.

Explanation:

Archaea play an important role in ecosystems with organisms that derive or produce energy from oxidation of methane. Many of Archaea are bacteria which are often a major source of methane in such environments and they can play a role as primary producers. Archaea is important for scientists because it has unique ecological roles and can also generate energy differently i.e. responsible for producing biological methane which no eukaryotes or bacteria can do that.

What kind of claim type does this statement make? Abbey Road is a much better album than Let It Bleed.

Select one:
a.
value
b.
policy
c.
fact

Answers

A . Value because that’s your valued opinion

The kind of claim type does this statement is the value claim.

A claim of value refered to something as either good or bad, or that one thing is better than another thing.

Example of value: Abbey road album is better than let it bleed.

Conclusively we can therefore say that option A is the answer that best fit the statement above.

Learn more from

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One of the distinguishing characteristics of nervous tissue is how difficult it is to repair damage to nervous tissue. Explain factors limit neurogenesis in the CNS of adults, why is it so hard to repair a damaged nerve

Answers

Answer:

Inhibitory influences from neuroglia, and the absence of growth-stimulating cues.

Explanation:

Neurogenesis in adults is limited by Inhibitory influences from neuroglia, mainly from oligodendrocytes, and the absence of growth-stimulating cues that are present during fetal development. It is so hard to repair a damaged nerve because nerve cell like other cells can't divide and increase in number, they can't renew themselves. Due to no division, the nerve cells does not increase in number and therefore can't repair themselves.

hormones stimulate certain endocrine glands to secrete hormones.

Answers

Answer:

hope its helps you

Explanation:

please like and mark brainlis

Endocrine gland/ source of hormone Hormone Target organ or tissue
Anterior pituitary (adenohypophysis) ACTH (adrenocorticotrophic hormone) Adrenal cortex
FSH (follicle stimulating hormone) Ovaries / testes (tubules)
LH (luteinizing hormone) Ovaries / testes (Leydig cells)
GH (growth hormone)

You have a microorganism you know is both fastidious and which normally lives in human lungs. Which medium might this organism have the highest probability of growing on and why

Answers

Answer:

It is likely that this microorganism grows in enriched culture media.

Explanation:

As shown in the question above, the microorganism that lives in the lungs is extremely demanding. This means that this microorganism is very difficult to be cultivated in a culture medium, as it requires specific nutrients and in specific amounts to be able to develop. These microorganisms are called fastidious microorganisms and need an enriched culture medium to develop.

Enriched culture media are those that have a high range of nutrients in their composition. These culture media are highly nutritious and for this reason, they are the ideal environment for demanding microorganisms, as it can efficiently meet the needs of this organism.

Complete the comparison of the metabolic pathways leading to thymine in DNA and thymine as a modified base in tRNA.

Thymine in DNA occurs as the result of thymidylate synthase creating _______________ , which then undergoes ____________ to ____________, then to __________, and incorporated into DNA by ___________.

Answers

Answer:

The question is incomplete, the complete question is as follow:

Thymine in DNA occurs as the result of thymidylate synthase creating _______, which then undergoes _______ to _______, then to _______, and incorporated into D N A by _______. Thymine in tRNA arises ________, by an S-adenosylmethionine-dependent _______ of a ______ residue in RNA.

Answer:

Thymine in DNA occurs as the result of thymidylate synthase creating dTMP, which then undergoes phosphorylation to dTDP, then to dTTP, and incorporated into DNA by DNA polymerase. Thymine in tRNA arises posttranslationally, by an S-adenosylmethionine-dependent methylation of a UMP residue in RNA.

Explanation:

Thymidylate synthase is a key enzyme that catalyzes the synthesis of 2′-deoxythymidine-5′-monophosphate (dTMP) from 2′-deoxyuridine-5′-monophosphate (dUMP). This enzyme catalyzes the addition of a phosphate group (phosphorylation) of dTMP in order to form thymidine 5'-diphosphate (dTDP). Once synthesized, dTMP can be metabolized to deoxythymidine triphosphate (dTTP), which is a precursor for DNA biosynthesis. On the other hand, transfer ribonucleic acid (tRNA) is methylated after the molecule is synthesized. The transfer of the methyl group is catalyzed by an S-adenosylmethionine–dependent methyltransferase that catalyzes the methylation of uridine monophosphate (UMP) using SAM (S-adenosylmethionine) as the methyl donor.

Which structures allow lycophytes to grow bigger than mosses and liverworts?
A. gametophytes and sporophytes
b. xylem and phloem
C. haploid and diploid
D. roots and stems

Answers

The structure that allows lycophytes to grow bigger than mosses and liverworts is xylem and phloem which is option B

Lycophytes are spore bearing vascular plants. Being a vascular plant, they possess vessels ( vascular tissues) which include:

ylem: this is used for conducting water usually from the root to the rest of the plant partsPhloem: this is the vascular tissue that is used to conduct food( sugar) produced in the leaves of plants to other parts of the plant.

The possession of the vessels makes the lycophytes appear bigger.

Mosses and liverworts belongs to the plant phylum Bryophyta. They do not have any vascular tissues that can be used to conduct water and food. This restricts their size.

Therefore, the structure that allows lycophytes to grow bigger than mosses and liverworts is xylem and phloem

Learn more about xylem and phloem here:

https://brainly.com/question/2002070

Answer:

xylem and phloem

Explanation:

Lycophytes have specialized tissue that transports nutrients and provides structural support.

A student wants to determine how his classmates feel about school. He does a survey away from school so all participants will be willing to answer freely. In several cases, younger siblings of his classmates are present, so he lets them take the survey too. He surveys a total of 50 students. Has he done a well-designed, controlled experiment

Answers

Answer:

ojjjososkjsjeiemejekliijahaupamahdh

What is the answer with explaining

Answers

Answer:

EeWw

Explanation:

This question involves two genes; one coding for earlobes and the other for hairline. According to the question, one parent is homzygous recessive for earlobe but homzygous dominant for hairline i.e. (eeWW) while the other parent is homzygous dominant for unattached earlobes but homzygous recessive for hairline i.e. (EEww).

The cross between the two parents is as follows: eeWW × EEww. The following gamete combination will be produced by each parent:

eeWW - eW, eW, eW, eW

EEww - Ew, Ew, Ew, Ew

Using these gametes in a punnet square, the following proportions of offsprings will likely be produced:

All EeWw offsprings

explain how the mammalian skin perform it's role as a thermoregulatory



Answers

Answer:

The skin contains many blood capillaries and sweat glands ,the sweat glands secrete sweat when it is hot.when the sweat evaporates from the skin it cools the body.thermoregulation by the skin occurs through dilation and constriction of the blood vessels.when the bodies temperature raises,the blood vessels carry heat in the blood to the skin.the blood capillaries dilate become wider so that more heat can be lost to the environment.this is called vasodilation.when the outside temperature is low,the blood capillaries constrict become narrower so that less blood flows to the surface of the skin.therefore less heat is lost to the environment this is called vasoconstriction.

I hope this helps

Bert has blonde hair (b). Molly has brown hair (B), but her genotype is Bb, meaning she carries a recessive blonde allele. What is the likelihood of Bert and Molly's second child having brown hair?

Answers

Answer:

50%

Explanation:

Iif you do a punnet square you get Bb, Bb, bb, and bb

since blond is represneted by the recessive bb it's a 50% the child will have blond hair

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